헥산디올(1,2)

헥산디올(1,2) 속성

헥산디올(1,2) MSDS

DL-1,2-Hexanediol

헥산디올(1,2) C화학적 특성, 용도, 생산

개요

헥산의 1,2번 탄소에 두개의 히드록시를 갖는 다이올 형태로 보습성과 항균성이 우수함.

용도

자극이 거의 없어 화장품이나 천연 추출물의 보존제로 널리 쓰이고 있음물, 알콜에 대한 상용성이 우수.

개요

1,2-Hexanediol is a linear aliphatic diol with a carbon chain length containing six carbons. It is a synthetic preservative and moisture-binding agent belonging to a class of agents known as higher molecular glycols. It is considered non-sensitizing. It is ideal for use as an emollient, humectant, and wetting agent in cosmetic and skin care products.

화학적 성질

clear colorless to light yellow liquid.

용도

DL-1,2-Hexanediol is a solvent used to dissolve other compounds in a formulation.

제조 방법

1,2-Hexanediol was synthesized with an overall yield of approximately 45% using a multi-step process that involved a-bromination of caproic acid, followed by hydrolysis to a-hydroxycaproic acid, and concluded with reduction using lithium aluminum hydride. In an alternate method, the organic acid was oxidized with H2O2 to form a peroxy acid, which in turn epoxidized the olefin double bond and ultimately underwent hydrolysis to yield 1,2-hexanediol.
SYNTHESIS OF SOME HEXANEDIOLS

주요 응용

1,2-Hexanediol has an antibacterial effect. Other uses are in ink-jet inks, fuel and lubricant additives.

benefits

1,2 hexanediol is most commonly used as a solvent in skincare formulation. It pulls the moisture up from the deeper levels of the skin, as well as from the air, to help keep the top layers of your skin from drying out. This makes It very effective at keeping your skin hydrated and providing long-term moisture. It can also help to disperse pigments more evenly in makeup products and boost the antimicrobial activity of preservatives.

일반 설명

1,2-Hexanediol acts as cosurfactant, used for modifying the sodium dodecyl sulfate micelles. Solubility of 1,2-hexanediol in supercritical CO₂ has been reported. It has a tendency of self-association to form micelle-like aggregates.

Safety

1,2-Hexanediol is safe for skin and hair when used in lower concentrations. In an in-use safety evaluation for skin irritation and sensitization potential, 28 participants (males and females) were instructed to use a body wash containing 0.15% 1,2- hexanediol for a minimum of 3 times per week over a 30-day period. There was no evidence of erythema, edema, or dryness of application sites in any of the participants, and it was concluded that the product did not demonstrate a potential for eliciting skin irritation or sensitization.
Safety Assessment of 1,2-Glycols as Used in Cosmetics

Purification Methods

Fractionally distil it, preferably in a vacuum. Alternatively, dissolve it in Et2O, dry with K2CO3 then Na2SO4, filter, evaporate and distil it in a vacuum. The bis-4-nitrobenzoyl derivative has m 101.5-102.5o. [Rudloff Can J Chem 36 486 1958, Beilstein 1 I 251, 1 III 2200, 1 IV 2554.]

헥산디올(1,2) 준비 용품 및 원자재

원자재

준비 용품

헥산디올(1,2) 공급 업체

공급자	전화	이메일	국가	제품 수	이점
weifang runzhong fine chemical co., ltd	536-7868377 +8618653686003	sq@runzhongchem.com	China	187	58
Baynoe Chem (Suzhou) Co., Ltd.	+86-512 65869404 +86-18934593683	sales06@baynoe.com	China	292	58
Suzhou Yuanrui Bio-Tech Co., Ltd	+86-18106132862 +86-18106132862	sales02@yuanruibio.com	China	278	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-13102810335	admin@hbsaisier.cn	China	424	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15371	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
Jiangsu Qingquan Chemical Co., Ltd.	+86-571-86589381,86589382,86589383	sales1@qqpharm.com	CHINA	154	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55

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