눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2
0
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide C화학적 특성, 용도, 생산
개요
VUF8430 is a histamine H4 receptor agonist (Ki = 31.6 nM). It is selective for histamine H4 over H1 and H3 receptors in radioligand binding assays (Kis = >1 and 1 μM, respectively) and is less active in isolated guinea pig atria, which endogenously expresses high levels of H2 receptors (pD2 = 3.8). VUF8430 inhibits forskolin-induced, cAMP-mediated increases in β-galactosidase activity (EC50 = 50.1 nM). In vivo, VUF8430 (30 mg/kg) enhances HCl-induced formation of gastric lesions in rats. It also reduces mechanical and thermal allodynia in a mouse model of peripheral neuropathy induced by spared nerve injury (SNI).
용도
VUF 8430 Dihydrobromide is an H4 receptor agonist.
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide 준비 용품 및 원자재
원자재
준비 용품
2-(diaminomethylideneamino)ethylsulfanylmethanimidamide dihydrobromide 공급 업체
