OXYPHENYL BUTAZONE
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OXYPHENYL BUTAZONE 속성
- 녹는점
- 109-111°C
- 끓는 점
- 462.71°C (rough estimate)
- 밀도
- 1.2118 (rough estimate)
- 굴절률
- 1.6140 (estimate)
- 저장 조건
- -20°C
- 용해도
- DMSO: 용해성10mg/mL, 투명
- 산도 계수 (pKa)
- pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
- 물리적 상태
- 가루
- 색상
- 흰색에서 갈색으로
- 수용성
- 20mg/L(상온)
- 안정성
- 흡습성
- CAS 데이터베이스
- 129-20-4(CAS DataBase Reference)
- IARC
- 3 (Vol. 13, Sup 7) 1987
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,N | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-50 | ||
| 안전지침서 | 61 | ||
| 유엔번호(UN No.) | UN 3077 9 / PGIII | ||
| WGK 독일 | 3 | ||
| 유해 물질 데이터 | 129-20-4(Hazardous Substances Data) |
OXYPHENYL BUTAZONE C화학적 특성, 용도, 생산
화학적 성질
Light Beige Solid용도
Anti-inflammatory;Cyclooxygenase inhibitoIndications
Oxyphenbutazone (Oxalid, Tandearil) is the principal uricosuric metabolite of phenylbutazone. It has the same indications and toxicities as phenylbutazone.정의
ChEBI: A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following asso iation with blood dyscrasis and Stevens-Johnson syndrome.World Health Organization (WHO)
Oxyphenbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1955 for the treatment of rheumatic disorders. It is one of the active metabolites of phenylbutazone and has a similar spectrum of activity including an association with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring antiinflammatory agents. Although oxyphenbutazone has been widely withdrawn it remains available in some countries.일반 설명
Oxyphenbutazone is a derivative compound of phenylbutazone. Oxyphenbutazone is one of the metabolites formed in the liver following administration of phenylbutazone. Given orally it causes fewer gastrointestinal adverse effects than phenylbutazone and is used at 300 – 400 mg/d for the same indications as the parent drug.OXYPHENYL BUTAZONE 준비 용품 및 원자재
원자재
준비 용품
OXYPHENYL BUTAZONE 공급 업체
글로벌( 68)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 |
1056@dideu.com | China | 3632 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 29271 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9116 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32360 | 55 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| LGM Pharma | 1-(800)-881-8210 |
inquiries@lgmpharma.com | United States | 2127 | 70 |
OXYPHENYL BUTAZONE 관련 검색:
1,2-디페닐히드라진 1-아세틸-2-페닐히드라진 4-메틸-1-페닐-3-피라졸리돈 1-페닐-3-피라졸리돈 페닐부타존
OXYPHENYL BUTAZONE
ISOBUTYL HYDRAZINE SULFATE
MOFEBUTAZONE
OXYPHENYL BUTAZONE MONOHYDRATE
1,2-Diformylhydrazine
Isobutyric acid hydrazide
4-butyl-2-phenyl-1-[4-(phenylmethoxy)phenyl]pyrazolidine-3,5-dione
gamma-hydroxyphenylbutazone
1,2-DIPHENYL-PYRAZOLIDINE-3,5-DIONE
HEXANOICACIDHYDRAZIDE
N-BUTYRYL-P-AMINOPHENOL
N-(4-hydroxyphenyl)pentanamide
N,N'-dimethylmalonamide