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OXYPHENYL BUTAZONE

OXYPHENYL BUTAZONE 구조식 이미지
카스 번호:
129-20-4
상품명:
OXYPHENYL BUTAZONE
동의어(영문):
bm1;BM 1;Flogal;Frabel;g27202;Iridil;Mysite;Neofen;Oxalid;Reumox
CBNumber:
CB2133346
분자식:
C19H20N2O3
포뮬러 무게:
324.37
MOL 파일:
129-20-4.mol

OXYPHENYL BUTAZONE 속성

녹는점
109-111°C
끓는 점
462.71°C (rough estimate)
밀도
1.2118 (rough estimate)
굴절률
1.6140 (estimate)
저장 조건
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
용해도
DMSO: soluble10mg/mL, clear
산도 계수 (pKa)
pKa 4.7/10.0±0.2(H2O,t =25,Iundefined) (Uncertain)
물리적 상태
powder
색상
white to brown
CAS 데이터베이스
129-20-4(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N
위험 카페고리 넘버 22-50
안전지침서 61
유엔번호(UN No.) UN 3077 9 / PGIII
WGK 독일 3
그림문자(GHS):
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H400 수생생물에 매우 유독함 수생 환경유해성 물질 - 급성 구분 1 경고 P273, P391, P501
예방조치문구:
P273 환경으로 배출하지 마시오.

OXYPHENYL BUTAZONE C화학적 특성, 용도, 생산

화학적 성질

Light Beige Solid

용도

Anti-inflammatory;Cyclooxygenase inhibito

정의

ChEBI: A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following asso iation with blood dyscrasis and Stevens-Johnson syndrome.

상표명

Tandearil (Novartis);Algi-tandril;Anarreumol-b;Artzone;Buteril;Campozim;Defolgin;Difmedol;Dolo-phlogase;Dolo-tandril;Fibutrox;Gp 40705;Iltazon;Iltoxon;Inflamil;Mindaril;Miyadril;Oflamin;Otone;Oxybutazone;Oxybutol;Oxyperol;Oxyphenbutone;Phlogistol;Phlogont;Phloguran;Pilabutina;Realin;Rheumapax;Segudol;Suganril;Tanal;Tandacot;Teneral;Vefren.

World Health Organization (WHO)

Oxyphenbutazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1955 for the treatment of rheumatic disorders. It is one of the active metabolites of phenylbutazone and has a similar spectrum of activity including an association with serious and sometimes fatal adverse reactions, notably cases of aplastic anaemia and agranulocytosis. Many national drug regulatory authorities consider that more recently introduced drugs offer a safer alternative for most, if not all, patients requiring antiinflammatory agents. Although oxyphenbutazone has been widely withdrawn it remains available in some countries.

OXYPHENYL BUTAZONE 준비 용품 및 원자재

원자재

준비 용품


OXYPHENYL BUTAZONE 공급 업체

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