피퍼롱구미닌

피퍼롱구미닌
피퍼롱구미닌 구조식 이미지
카스 번호:
5950-12-9
한글명:
피퍼롱구미닌
동의어(한글):
피퍼롱구미닌;피페론구민
상품명:
piperlonguminine
동의어(영문):
MEXE;mexedrone;Piperlonguminin;Piperlonguminine;N-Isobutylpiperamide;Mexedrone MEXE MDPHP BK-2CB;Piperlonguminine, 10 mM in DMSO;Mexedrone Cas no.: 5950-12-9 White crystal 99%;5-benzo[1,3]dioxol-5-yl-N-(2-methylpropyl)penta-2,4-dienamide;(2E,4E)-5-(1,3-benzodioxol-5-yl)-N-isobutyl-penta-2,4-dienamide
CBNumber:
CB21562460
분자식:
C16H19NO3
포뮬러 무게:
273.33
MOL 파일:
5950-12-9.mol

피퍼롱구미닌 속성

녹는점
l66-8°C
저장 조건
Store at -20°C
용해도
≤3mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
물리적 상태
결정질 고체
색상
White to off-white
InChI
InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+
InChIKey
WHAAPCGHVWVUEX-GGWOSOGESA-N
SMILES
C(NCC(C)C)(=O)/C=C/C=C/C1=CC=C2OCOC2=C1

안전

피퍼롱구미닌 C화학적 특성, 용도, 생산

개요

Piperlonguminine is an alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties. Piperlonguminine (3-12.5 μM) has been shown to dose dependently decrease expression of amyloid precursor protein and amyloid-β peptide in human neuroblastoma cells, suggesting it may have implication in treating Alzheimer’s disease.

생물학적 활성

Piperlonguminine is an alkaloid amide isolated from the Piper species. It has a wide range of biological properties including anti-inflammatory, anti-tumour, neuroprotective, anti-platelet, anti-melanogenic, anti-fungal and antibacterial activities. In addition, its derivative piperlonguminine acid has Antihyperlipidemic activity.

참고 문헌

Chatterjee, Dutta., Tetrahedron Lett., 1797 (1966)
Chatterjee, Dutta., Tetrahedron, 23, 1769 (1967)

피퍼롱구미닌 준비 용품 및 원자재

원자재

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