크리스탈 바이올렛

크리스탈 바이올렛
크리스탈 바이올렛 구조식 이미지
카스 번호:
548-62-9
한글명:
크리스탈 바이올렛
동의어(한글):
젠티안바이올렛;크리스탈바이올렛;크리스탈바이올렛CrystalViolet;젠티안바이올렛용액;크리스탈바이올릿;메틸바이올렛;염기성자색1호(메틸바이올렛);염기성자색3호(크리스탈바이올렛)
상품명:
Crystal Violet
동의어(영문):
GENTIAN VIOLET;Methyl violet;304;gentian;BASIC VIOLET 3;METHYLROSANILINE;METHYLROSANILINE CHLORIDE;METHYL VIOLET 10B;methylviolett;Crystal violent
CBNumber:
CB2161846
분자식:
C25H30ClN3
포뮬러 무게:
407.99
MOL 파일:
548-62-9.mol
MSDS 파일:
SDS

크리스탈 바이올렛 속성

녹는점
205 °C (dec.) (lit.)
끓는 점
560.86°C (rough estimate)
밀도
1.19 g/cm3 at 20 °C
증기압
0Pa at 25℃
굴절률
1.6010 (estimate)
인화점
40 °C
저장 조건
room temp
용해도
물: 27°C에서 용해성50g/L
색상 색인 번호
42555
산도 계수 (pKa)
9.4(at 25℃)
물리적 상태
고체
물리적 상태
단단한 모양
색상
S. 번호: 785
pH 범위
0.8(yellow)-2.6(blue/violet)
냄새
약간의 독특한 냄새
수소이온지수(pH)
2.5-3.5 (10g/l, H2O, 20℃)
수용성
16g/L(25℃)
최대 파장(λmax)
590nm
Merck
14,4395
BRN
4077708
안정성
안정적인. 강한 산화제, 강산과 호환되지 않습니다. 감광성. 타기 쉬운.
생물학 분야의 응용
Detecting microorganisms; treating atopic dermatitis,dermatological diseases,28,skin wounds,lesions,hemorrhoids,1,multiple myeloma,Non-Hodgkin’s lymphoma,breast cancer,neurodegenerative diseases,onychomycosis; wound dressing
주요 응용
Photoresists, lithographic printing plate, printed circuit board, inks, hair dyes, shampoo, drug screening method, bone cement preparation method, microorganisms, hemorrhoids, antifungal, antibacterial, antimalarial agent, dental application
InChIKey
ZXJXZNDDNMQXFV-UHFFFAOYSA-M
LogP
1.172 at 25℃
CAS 데이터베이스
548-62-9(CAS DataBase Reference)
EPA
Crystal violet (548-62-9)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N,T,C
위험 카페고리 넘버 52/53-50/53-45-41-22-40-34-10-36/37/38-23/25-51/53-68
안전지침서 61-60-53-45-46-36/37/39-26-39-36/37-16-22
유엔번호(UN No.) UN 3077 9/PG 3
WGK 독일 3
RTECS 번호 BO9000000
TSCA Yes
위험 등급 9
포장분류 III
HS 번호 32041300
유해 물질 데이터 548-62-9(Hazardous Substances Data)
독성 LD50 orally in mice, rats: 1.2, 1.0 g/kg (Hodge)
기존화학 물질 KE-07006
중점관리물질 필터링 별표1-86
그림문자(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 눈에 심한 손상을 일으킴 심한 눈 손상 또는 자극성 물질 구분 1 위험 GHS hazard pictograms P280, P305+P351+P338, P310
H350 암을 일으킬 수 있음 (노출되어도 암을 일으키지 않는다는 결정적인 증거가 있는 노출경로가 있다면 노출경로 기재) 발암성 물질 구분 1A, 1B 위험 GHS hazard pictograms
H410 장기적 영향에 의해 수생생물에 매우 유독함 수생 환경유해성 물질 - 만성 구분 1 경고 GHS hazard pictograms P273, P391, P501
예방조치문구:
P202 모든 안전 조치 문구를 읽고 이해하기 전에는 취급하지 마시오.
P273 환경으로 배출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P308+P313 노출 또는 접촉이 우려되면 의학적인 조치· 조언를 구하시오.
NFPA 704
0
2 0

크리스탈 바이올렛 MSDS


Methyl violet

크리스탈 바이올렛 C화학적 특성, 용도, 생산

개요

Crystal Violet is light sensitive. May react vigorously with strong oxidizing agents. May react exothermically with reducing agents to release gaseous hydrogen.

화학적 성질

dark green powder or crystals

출처

Gentian is a fl owering perennial found in Europe and Asia.

용도

Crystal Violet is used as an acid-base indicator, an alcohol denaturant, a biological stain, a textile dye and an indicator for copper salts. It is a component of gram staining in microorganisms and cell lines.

제조 방법

It is manufactured through using N, N-dimethylaniline as raw materials, followed by condensation, addition, chlorination and other reactions. Alternatively, it can be synthesized through the reaction between Michler ketone and N, N-dimethylaniline reaction in the presence of phosphorus oxychloride, followed by azeotropic reaction with hydrochloric acid. 548-62-9 synthesis Recrystallization in hot water will generate compound containing nine crystal water molecules.

Essential oil composition

A number of bitter compounds present in gentian are primarily amarogentin (strongly bitter), gentiopricin (approximately 1.5% in fresh root), swertiamarin and gentiopricroside. The leaves and flowers contain mainly xanthones. Secoiridoids and flavonoids were also detected. In the phase of flowering, leaves are rich with compounds possessing C-glycoside structures while O-glycoside structures accumulate mainly before flowering.

일반 설명

It belongs to triamino-triphenylmethane synthetic dyes; alkaline. It is an important dye used in bacterial Gram stain. The mixed reagent of crystal violet chloride and iodine is known as gentian violet.

공기와 물의 반응

Insoluble in water.

화재위험

Flash point data for Crystal Violet are not available, however, Crystal Violet is probably combustible.

Clinical Use

Gentian violet is variously known as hexamethyl-p-rosanilinechloride, crystal violet, methyl violet, and methylrosanilinechloride. It occurs as a green powder or greenflakes with a metallic sheen. The compound is soluble inwater (1:35) and alcohol (1:10) but insoluble in nonpolar organicsolvents. Gentian violet is available in vaginal suppositoriesfor the treatment of yeast infections. It is also used asa 1% to 3% solution for the treatment of ringworm and yeastinfections. Gentian violet has also been used orally as an anthelminticfor strongyloidiasis (threadworm) and oxyuriasis.

Safety Profile

Poison by ingestion, intravenous, and intraperitoneal routes, An experimental teratogen. Other experimental reproductive effects. A human sktn irritant. Human mutation data reported. Questionable carcinogen with experimental carcinogenic data. When heated to decomposition it emits very toxic fumes of NO, and Cl-.

Purification Methods

Crystallise the dye from water (20mL/g), the crystals being separated from the chilled solution by centrifugation, then wash them with chilled EtOH (solubility is 1g in 10 mL of hot EtOH) and diethyl ether and dry under vacuum. It is soluble in CHCl3 but insoluble in Et2O. The carbinol is precipitated from an aqueous solution of the dye-hydrochloride, using excess NaOH, then dissolve in HCl and recrystallise it from water as the chloride [UV and kinetics: Turgeon & La Mer J Am Chem Soc 74 5988 1952]. The carbinol base has m 195o (needles from EtOH). The diphthalate (blue and turns red in H2O) crystallises from H2O, m 153-154o(dec at 185-187o)[Chamberlain & Dull J Am Chem Soc 50 3089 1928]. [Beilstein 13 H 233, 13 IV 2284.]

크리스탈 바이올렛 준비 용품 및 원자재

원자재

준비 용품


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