Alizapride
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Alizapride 속성
- 녹는점
- 139°
- 끓는 점
- 580.3±40.0 °C(Predicted)
- 밀도
- 1.224±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C(protect from light)
- 산도 계수 (pKa)
- 7.09±0.40(Predicted)
- CAS 데이터베이스
- 59338-93-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 독성 | LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau) |
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| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Alizapride C화학적 특성, 용도, 생산
Originator
Plitican ,Delagrange ,France ,1981Manufacturing Process
38.6 g (0.2 mol) of 2-methoxy-4,5-azimidobenzoic acid were dissolved in anhydrous toluene and 56 g (0.4 mol) of 1-allyl-2-amino-methylpyrrolidine were added. The mixture was heated to 50°C and then 42 g (0.3 mol) of phosphoric anhydride were added. The mixture was warmed at reflux temperature for 3 hours and then cooled to 80°C. After adding water, the aqueous layer was alkalized. The crystals were filtered, washed with water and then dissolved in 450 ml of acetone. After crystallization, the product was 40.4 g (yield 65%) of N-(1'-allyl-2'-pyrrolidylmethyl)-2-methoxy-4,5- azimidobenzamide having a melting point of 139°C were obtained.Therapeutic Function
Neuroleptic, AntiemeticAlizapride 준비 용품 및 원자재
원자재
2-aminomethyl-N-allylpyrrolidine
2-(Aminomethyl)-1-N-Boc-pyrrolidine
Alizapride hydrochloride
Methyl 4-amino-2-methoxybenzoate
벤조트리아졸
메틸에틸케톤
Anhydrous toluene
1H-벤조트라이아졸-6-카복실산
오산화 인
피롤리딘
1-Allyl-2-aminomethylpyrrolidine
준비 용품
Alizapride 공급 업체
글로벌( 45)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 |
xie@china-sinoway.com | China | 992 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |
| Mainchem Co., Ltd. | +86-0592-6210733 |
sale@mainchem.com | China | 32360 | 55 |
| Chemwill Asia Co.,Ltd. | 86-21-51086038 |
chemwill_asia@126.com | CHINA | 23931 | 58 |
| LGM Pharma | 1-(800)-881-8210 |
inquiries@lgmpharma.com | United States | 2127 | 70 |