Clomipramine hydrochloride
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Clomipramine hydrochloride 속성
- 녹는점
- 189-190°C
- 인화점
- 9℃
- 저장 조건
- 2-8°C
- 용해도
- H2O: 25 mg/mL
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- 수소이온지수(pH)
- 3.5～5.0（100g/l，25℃）
- BCS Class
- 3/1
- InChIKey
- WIMWMKZEIBHDTH-UHFFFAOYSA-N
- CAS 데이터베이스
- 17321-77-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn,T,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 20/21/22-39/23/24/25-23/24/25-11-36/37/38 | ||
| 안전지침서 | 36-45-36/37-16-7-62-38-36/37/39-28-26-24/25-22-20/21-13 | ||
| 유엔번호(UN No.) | 3249 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | HN9055000 | ||
| 위험 등급 | 6.1(b) | ||
| 포장분류 | III | ||
| HS 번호 | 2933996100 |
Clomipramine hydrochloride C화학적 특성, 용도, 생산
개요
Clomipramine is a tricyclic antidepressant, the 3-화학적 성질
Off-White Solid용도
Serotonin reuptake inhibitor. Antidepressant; antiobsessional agent정의
ChEBI: A hydrochloride resulting from the reaction of equimolar amounts of clomipramine and hydrogen chloride. One of the more sedating tricyclic antidepressants, it is used for the treatment of depression as well as obsessive-compulsive disorder and phobias.일반 설명
Clomipramine (Anafranil) is up to 50 times as potentas imipramine in some bioassays. This does not implyclinical superiority, but it might be informative about tricyclicand, possibly, other reuptake inhibitors. The chloro replacingthe H-substituent could increase potency by increasingdistribution to the CNS, but it is unlikely that this wouldgive the potency magnitude seen. It might be conjecturedthat an H-bond between the protonated amino group (as invivo) and the unshared electrons of the chloro substituent might stabilize a β-arylamine–like shape and give moreefficient competition for the transporter. The drug is anantidepressant. It is used in obsessive–compulsive disorder,an anxiety disorder that may have an element of depression.생물학적 활성
Potent, selective 5-HT uptake blocker. Antidepressant. Binds to the human 5-HT transporter with a K i of 0.05 nmol/l. Also available as part of the Serotonin Uptake Inhibitor Tocriset™ .Clomipramine hydrochloride 준비 용품 및 원자재
원자재
준비 용품
Clomipramine hydrochloride 공급 업체
글로벌( 352)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 |
admin@hbouhuang.com | China | 1696 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Hubei XinRunde Chemical Co., Ltd. | +8615102730682 |
bruce@xrdchem.cn | CHINA | 566 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |