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ABT 263

ABT 263 구조식 이미지
카스 번호:
923564-51-6
상품명:
ABT 263
동의어(영문):
ABT 263;Navitoclax;Navitoclax, >=98%;ABT-263,Navitoclax;Navitoclax (ABT-263);BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe;ABT 263, 98%, potent inhibitor of Bcl-xL,Bcl-2 and Bcl-w;(S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperaz;(R)-4-(4-((2-(4-Chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morph;(R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonyl)benzamide
CBNumber:
CB21872884
분자식:
C47H55ClF3N5O6S3
포뮬러 무게:
974.61
MOL 파일:
923564-51-6.mol

ABT 263 속성

녹는점
114-116°C
밀도
1.41±0.1 g/cm3(Predicted)
저장 조건
-20°C Freezer, Under Inert Atmosphere
산도 계수 (pKa)
4.60±0.10(Predicted)
CAS 데이터베이스
923564-51-6

안전

HS 번호 29339900

ABT 263 C화학적 특성, 용도, 생산

화학적 성질

Pale Yellow Solid

용도

ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.

용도

A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.

ABT 263 준비 용품 및 원자재

원자재

준비 용품


ABT 263 공급 업체

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