D(+)-Raffinose pentahydrate

D(+)-Raffinose pentahydrate 구조식 이미지
카스 번호:
17629-30-0
상품명:
D(+)-Raffinose pentahydrate
동의어(영문):
RAFFINOSE PENTAHYDRATE;D-RAFFINOSE PENTAHYDRATE;β-D-fructofuranoside;MELITOSE;D-(+)-RAFFINOSE;Raffinose, 99%+;RAFFINOSE, 5-HYDRATE;D-(+)-Raffinose Melitose, Melitriose;MELITOSE PENTAHYDRATE
CBNumber:
CB2230061
분자식:
C18H42O21
포뮬러 무게:
594.51
MOL 파일:
17629-30-0.mol
MSDS 파일:
SDS

D(+)-Raffinose pentahydrate 속성

녹는점
78-80 °C
알파
105 º (c=10,water,dry basis)
끓는 점
78-82℃
밀도
1.465
저장 조건
Inert atmosphere,Room Temperature
용해도
H2O: 50 mg/mL
물리적 상태
가루
색상
하얀색
냄새
냄새 없는
optical activity
[α]20/D +105±2°, c = 10% in H2O
수용성
143g/L
감도
Hygroscopic
Merck
14,8096
BRN
4285763
안정성
흡습성
InChIKey
BITMAWRCWSHCRW-PFQJHCPISA-N
CAS 데이터베이스
17629-30-0(CAS DataBase Reference)
EPA
.alpha.-D-Glucopyranoside, .beta.-D-fructofuranosyl O-.alpha.-D-galactopyranosyl-(1.fwdarw.6)-, pentahydrate (17629-30-0)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/38
안전지침서 24/25-37/39-26
WGK 독일 3
RTECS 번호 LZ5851200
F 고인화성물질 3
TSCA Yes
HS 번호 29400000
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
1
1 0

D(+)-Raffinose pentahydrate C화학적 특성, 용도, 생산

개요

D-(+)-Raffinose is a trisaccharide composed of galactose, glucose, and fructose that occurs naturally in a variety of vegetables and grains. It is hydrolyzed to galactose and sucrose by α-galactosidase.

용도

D-(+)-Raffinose is a trisaccharide built from 1 mol each of D-galactose, D-glucose, and D-fructose which are obtained from it by acid hydrolysis. Invertase splits it into melibiose and saccharose. D- (+)-Raffinose occurs in Australian manna; in cottonseed meal.

생산 방법

Raffinose occurs naturally in Australian manna, cottonseed meal, and seeds of various food legumes. It can be isolated from beet sugar molasses through sucrose separation, seed-crystallization, and filtration.

Pharmaceutical Applications

Raffinose is a trisaccharide carbohydrate that is used as a bulking agent, blood substitute, stabilizing agent, and water scavenger in freeze-drying where it acts as a stabilizer for freeze-dried formulations. It is also used as a crystallization inhibitor in sucrose solutions.

Safety

Raffinose is a naturally occurring trisaccharide investigated for use in freeze-dried pharmaceutical formulations. It occurs in a number of plants that are consumed widely.

저장

Raffinose is stable under ordinary conditions of use and storage. Excessive heat should be avoided to prevent degradation. Thermal decomposition products are carbon monoxide and carbon dioxide.

Purification Methods

fructo-furanose [17629-30-0 (5H2O), 512-69-6 (anhydrous)] M 594.5, m 8 0o, 80 -82o, +124o (c 10, H2O), [ ] D +105o (c 1 for pentahydrate, H2O), pK 1 12.40, pK 2 13.44, pK 3 13.52. D(+)-Raffinose crystallises from H2O, 90% aqueous EtOH or MeOH as the pentahydrate. The anhydrous sugar has m 132-135o. It has RF 0.8 on TLC (Silica Gel, and 1:3:3 CHCl3/butanone:/MeOH). The undecaacetate has been purified through an alumina column by elution with CHCl3, and recrystallised from EtOH/MeOH/H2O (3:2:5), with m 99-100o, [] D +92.8o (c 5.14, EtOH). [pK : Coccioli & Vicedomini Ann Chim (Rome) 66 269, 275 1976, 1H NMR: Suami et al. Carbohydr Research 26 234 1973, Beilstein 17 III/IV 3801, 17/8 V 403.]

비 호환성

Raffinose is incompatible with strong oxidizers.

Regulatory Status

Raffinose is a naturally occurring trisaccharide and is consumed as part of a normal diet.

D(+)-Raffinose pentahydrate 준비 용품 및 원자재

원자재

준비 용품


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