Amiodarone-D4 HCl
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Amiodarone-D4 HCl 속성
- 인화점
- 9℃
- 저장 조건
- -20°C
- 용해도
- DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 5 mg/ml
- 물리적 상태
- 고체
- 안정성
- 흡습성이 매우 높음
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-23/24/25-39/23/24/25 | ||
| 안전지침서 | 7-16-36/37-45 | ||
| 유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
| WGK 독일 | 1 |
Amiodarone-D4 HCl C화학적 특성, 용도, 생산
개요
Amiodarone-d4 is intended for use as an internal standard for the quantification of amiodarone by GC- or LC-MS. Amiodarone is a class III antiarrhythmic agent, in that it prolongs both cardiac action potential and refractoriness by blocking potassium currents. It inhibits the voltage-gated potassium channel hERG, also known as KCNH2, with an IC50 value of 1 μM. In addition, amiodarone binds with high affinity to the sigma-1 opioid receptor, 3-β-hydroxysteroid Δ8Δ7 isomerase, and C-8 sterol isomerase (Kis = 1, 25, and 62 nM, respectively) and inhibits human thyroid hormone receptors α and β (IC50s = 0.6 and 0.65 μM, respectively). It also inhibits the cytochrome P450 (CYP) isoforms CYP2C8 and CYP3A4 in vitro at low micromolar concentrations.일반 설명
A Certified Spiking Solution?and stable-labeled internal standard for use in therapeutic drug monitoring analyses by LC/MS. Amiodarone, an antiarrhythmic agent marketed as Pacerone?, Cordarone?, Aratac, Atlansil, is monitored by clinical labs to ensure patients remain within the drug′s therapeutic range.Amiodarone-D4 HCl 준비 용품 및 원자재
원자재
준비 용품
Amiodarone-D4 HCl 공급 업체
글로벌( 31)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
| Artis Biotech Co. Ltd. | 19138486554 18582380095 |
sales@artisbio.com | China | 3066 | 58 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 |
wxf@sungening.com | China | 9506 | 60 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 02584622273; |
kexin.zhou@haolvbiotech.com | China | 3021 | 58 |
| Shenzhen Kaimingke Biotechnology Co., Ltd. | 181-26439142 18126439142 |
1144496688@QQ.COM | China | 170 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11289 | 58 |
| Energy Chemical | 021-58432009 400-005-6266 |
marketing1@energy-chemical.com | China | 44894 | 58 |
| Shanghai Ruipu Medical Technology Co., Ltd | 15895968936 |
1018762393@qq.com | China | 8192 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. ， | 028-83243028 19136088901 |
sinostandards@163.com | China | 5044 | 58 |
| Manhag Testing Technology Co., Ltd | 020-020-3846236 17688849268 |
2443244976@qq.com | China | 7775 | 58 |
Amiodarone-D4 HCl 관련 검색:
1-클로로-2-(다이에틸아민)에테인 하이드로클로라이드
1-Methoxy AMiodarone
3-(4-HYDROXY-3-IODOBENZOYL)-2-BUTYLBENZOFURAN
Amiodarone
Amiodarone hydrochloride
[[p-(2-methoxyethyl)phenoxy]methyl]oxirane
Desethyl Amiodarone Hydrochloride
N-Desethylamiodarone-D4 HCl
Bis Des-iodo amiodarone HCl(Amiodarone impurity)
(2-butylbenzofuran-3-yl) (4-methoxyphenyl) ketone
Amiodarone Impurity 13
2-Butyl-3-(3,5-Diiodo-4-hydroxy benzoyl) benzofuran
Di(N-desethyl) AMiodarone Hydrochloride
2-Butylbenzofuran
2-Butyl-3-(4-hydroxybenzoyl)benzofuran
Dideiodo AMiodarone Hydrochloride
Amiodarone Impurity 2
Amiodarone N-oxide