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NFPA 704
0
2
0
2,3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE C화학적 특성, 용도, 생산
용도
2,3-Bis(4-hydroxyphenyl)propionitrile is an estrogen receptor β and α specific with pro- and anti-nociceptive actions in mice.
정의
ChEBI: A nitrile that is acetonitrile in which one of the hydrogens is replaced by a 4-hydroxyphenyl group while a second hydrogen is replaced by a 4-hydroxybenzyl group. It is a specific agonist for estrogen receptor beta (ERbeta).
생물학적 활성
Highly potent estrogen ER β receptor agonist with a 70-fold selectivity over ER α (EC 50 values are 0.85 and 66 nM respectively). Relaxes mesenteric arteries in vitro .
2,3-BIS(4-HYDROXYPHENYL)-PROPIONITRILE 준비 용품 및 원자재