Roquinimex
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Roquinimex 속성
- 녹는점
- 200-204°
- 끓는 점
- 436.2±45.0 °C(Predicted)
- 밀도
- 1.357±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,2-8°C
- 용해도
- DMSO: 11mg/mL
- 산도 계수 (pKa)
- 4.50±1.00(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- Merck
- 14,8259
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Roquinimex C화학적 특성, 용도, 생산
개요
Roquinimex is an immunomodulator with diverse biological activities. In vivo, roquinimex (80 mg/kg) increases the number of myocardial MHC class II-expressing cells, the ratio of cytotoxic to helper T cells, and survival and decreases necrotic lesion area in a mouse model of murine coxsackievirus B3-induced myocarditis. It induces IFN-γ production, reduces TNF-α and IL-1β production, prevents the development of proteinuria, and ameliorates nephritis in a mouse model of chronic graft versus host disease (GVHD). Roquinimex (300 mg/kg) decreases colonic myeloperoxidase (MPO) activity and mucosal damage in a mouse model of colitis induced by dextran sulfate (DSS; ). It also decreases tumor weight and tumor blood flow in a von Hippel-Lindau (VHL) type 2a paraganglioma mouse xenograft model.용도
Biological response modifier; immunomodulator.생물학적 활성
Immunomodulator with stimulatory and antitumor properties. Inhibits in vivo apoptosis of T-cells and inhibits angiogenesis in rats in vivo .Roquinimex 준비 용품 및 원자재
원자재
3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-1-Methyl-2-oxo-
methyl 3-(N-methyl-N-phenylamino)-3-oxopropanoate
3-Quinolinecarboxylic acid, 1,2-dihydro-4-hydroxy-1-Methyl-2-oxo-, Methyl ester
1,2-DIHYDRO-4-HYDROXY-1-METHYL-2-OXO-3-QUINOLINECARBOXYLIC ACID ETHYL ESTER
N-methylisatoic anhydride
아이사토산 무수물
N-메틸아닐린
안트라닐산
준비 용품
Roquinimex 공급 업체
글로벌( 108)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 |
3bsc@sina.com | China | 15848 | 69 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 |
Sales-CN@TCIchemicals.com | China | 24539 | 81 |