4'-METHOXYVALEROPHENONE

4'-METHOXYVALEROPHENONE 속성

4'-METHOXYVALEROPHENONE C화학적 특성, 용도, 생산

제조 방법

To a solution of N-methoxy-N-methyl-2-pyridyl urethane (364.4 mg, 2 mmol) in THF (6 mL), p-methoxyphenylmagnesium bromide (0.25 m in THF, 8 mL, 2 mmol) was added dropwise over a period of 10 min at 0 °C under nitrogen atmosphere. Stirring was maintained for a further 5 min and then n-butyllithium (1.60 m in hexane, 1.5 mL, 2.4 mmol) was added directly to the mixture (one-pot process). The reaction mixture was stirred for 0.5 h, while warming to room temperature, and was then quenched with 1 n HCl (5 mL). After evaporation of the THF, the concentrated mixture was poured into 1 n HCl (30 mL) and the aqueous phase was extracted with dichloromethane (3*20 mL). The combined organic extracts were dried over MgSO4, filtered, and concentrated to dryness in vacuo. The crude product was purified by column chromatography on silica gel (EtOAc/n-hexane, 1:4) to give 369.1 mg (96%) of p-methoxyvalerophenone.

Synthesis Reference(s)

Chemistry Letters, 15, p. 165, 1986
Tetrahedron, 50, p. 11839, 1994 DOI: 10.1016/S0040-4020(01)89299-1

4'-METHOXYVALEROPHENONE 준비 용품 및 원자재

원자재

준비 용품

4'-METHOXYVALEROPHENONE 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Mainchem Co., Ltd.	+86-0592-6210733	sale@mainchem.com	China	32360	55
Yangzhou Siyu Chemical Co.,Ltd.	0514-87325867	sales@siyuchem.com	China	370	55
Yantai ShengKailun Chemical Technology Co., Ltd.	13356901049	3119594100@qq.com	China	7778	55
Shijiazhuang Qiyue Chemical Co. LTD	15369111890 15369111890	sjzqiyuekeji@163.com	China	246	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	17691182729 18161915376	1046@dideu.com	China	10008	58
Shanghai Haohong Scientific Co., Ltd.	400-400-8210725	malulu@leyan.com	China	40041	58
Liaocheng Lebote Biopharmaceutical Technology Co., Ltd	0635-893290 18663513896;	28698871@qq.com	China	8531	58

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