D(-)-Arginine
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D(-)-Arginine 속성
- 녹는점
- 226 °C (dec.) (lit.)
- 알파
- -28.5 º (c=8, 6 N HCl)
- 끓는 점
- 305.18°C (rough estimate)
- 밀도
- 1.2297 (rough estimate)
- 굴절률
- -23 ° (C=8, 6mol/L HCl)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 산성 수용액(약간), 물(약간) 에 용해됨
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 2.49±0.24(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- 녹는
- 감도
- Air Sensitive
- BRN
- 1725412
- InChIKey
- ODKSFYDXXFIFQN-SCSAIBSYSA-N
- LogP
- -0.999 (est)
- CAS 데이터베이스
- 157-06-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 36-36/37/38-20/21/22 | ||
안전지침서 | 26-36 | ||
WGK 독일 | 3 | ||
RTECS 번호 | CF1934220 | ||
F 고인화성물질 | 9 | ||
TSCA | Yes | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29252000 |
D(-)-Arginine C화학적 특성, 용도, 생산
개요
D-arginine is the D-form of arginine, which is a kind of amino acids. It can be reacted with hydrogen peroxide for non-enzymatic synthesis of nitric oxide. It has certain pharmacological activities. For example, its derivative, 1-deamino-8-D-arginine vasopressin is useful for the management of haemophilia and von Willebrand’s disease. It also has the potential to inhibit the proliferation of certain cancer cells. In biological research, D-arginine is frequently used in the studies of L-arginine/nitric oxide pathway as an inactive form of L-arginine.화학적 성질
white to light yellow crystal powde용도
Arginine is an essential amino acid found in food and plant sources, and many biological systems.D-Arginine is extensively used in studies on L-arginine/nitric oxide pathway as an inactive form of L-arginine, even in man.
D-Arginine is slightly soluble (in water) and a moderately acidic compound (based on its pKa). D-Arginine can be found in human epidermis and platelet tissues. Within the cell, D-arginine is primarily located in the peroxisome. D-Arginine specifically can inhibit arginine decarboxylase enzymes and also functions as a metabolite.
정의
ChEBI: A D-alpha-amino acid that is the D-isomer of arginine.참고 문헌
https://www.alfa.com/zh-cn/catalog/A16137/Iannucci, N. B., et al. "Antiproliferative effect of 1-deamino-8-D-arginine vasopressin analogs on human breast cancer cells." Future Medicinal Chemistry 3.16(2011):1987-1993.
Ripoll, Giselle, et al. "Angiostatic activity of 1-Deamino-8-D-Arginine vasopressin and novel peptide analogues in breast cancer cells." Cancer Research 68(2008).
Navarro, Eduardo, et al. "Toxicological and Pharmacological Effects of D-Arginine." Basic & Clinical Pharmacology & Toxicology97.3(2005):149-154.
D(-)-Arginine 준비 용품 및 원자재
원자재
준비 용품
D(-)-Arginine 공급 업체
글로벌( 512)공급 업체
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