Hemin
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Hemin 속성
- 녹는점
- 300 °C
- 저장 조건
- 2-8°C
- 용해도
- 1.4M NaOH: 가용성25mg/mL
- 물리적 상태
- 수정 같은
- 색상
- 검은색
- 수용성
- 실질적으로 불용성
- Merck
- 14,4644
- BRN
- 5229914
- 노출 한도
- ACGIH: TWA 1 mg/m3
NIOSH: TWA 1 mg/m3
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다. 타기 쉬운.
- InChIKey
- BTIJJDXEELBZFS-HXFTUNQESA-K
- SMILES
- [Cl-][Fe+3]123[N-]4C5C(C)=C(C=C)C4=CC4C(C)=C(C=C)C(=CC6=C(C)C(CCC(=O)[O-])=C(C=C7C(CCC(=O)[O-])=C(C)C(C=5)=N17)[N-]26)N3=4.[H+]
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 24/25-22-36-26 | ||
WGK 독일 | 3 | ||
RTECS 번호 | LJ8080000 | ||
F 고인화성물질 | 8 | ||
TSCA | Yes | ||
HS 번호 | 29349990 |
Hemin C화학적 특성, 용도, 생산
개요
Hemin is a metalloporphyrin compound with a relatively simple structure. It is formed by the complexation of a molecule of ferrous iron and protoporphyrin. It is an in vitro group substitute of natural heme and its chemical properties are similar to that of heme. Heme, an essential small molecule in living organisms, can be found abundantly in various organisms including animals, plants, microorganisms, and algae.화학적 성질
Hemin is a Dark purple crystalline powder or elongated needle-shaped crystal. It does not dissolve in water, but it can dissolve in acidic acetone and alkaline water. The molecular formula is C34H32ClFe(III)N4O4, and the molecular weight is 651.96. Hemin is mainly used as raw material for anti-anemia and anti-cancer drugs.주요 응용
Hemin is used for the following applications:To study bacterial strains and growth conditions
Used in short-term colony assays (the culture medium consists of hemin along with other components)
Cell transfections
It may be used in β-hematin formation assay for analyzing the inhibitory activity of MMV (Medicines for Malaria Venture) Malaria Box compounds against the formation of β-hematin.
용도
Hemin is used in cellular protection and control mechanism. It stimulates the synthesis of globulin. It is also used to study the bacterial strains and growth conditions, in the short-term colony assays and cell transfections. Further, it is used to treat the symptoms of various porphyrias. In addition, it is used in the preparation of agar medium for the bacteria culture.일반 설명
Heme is a small molecule present either free or bound to hemoglobin in the bloodstream of mammals. This is an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion called hemin.Purification Methods
Hemin is purified by recrystallisation from AcOH. Also, hemin (5g) is shaken in pyridine (25mL) till it dissolves, then CHCl3 (40mL) is added, the container is stoppered and shaken for 5minutes (releasing the stopper occasionally). The solution is filtered under slight suction, and the flask and filter are washed with a little CHCl3 (15mL). During this period, AcOH (300mL) is heated to boiling, and saturated aqueous NaCl (5mL) and conc HCl (4mL) are added. The CHCl3 filtrate is poured in a steady stream, with stirring, into the hot AcOH mixture and set aside for 12hours. The crystals are filtered off, washed with 50% aqueous AcOH (50mL), H2O (100mL), EtOH (25mL), Et2O and dried in air. [Fischer Org Synth Coll Vol III 442 1955, Beilstein 26 III/IV 3048.]Hemin 준비 용품 및 원자재
원자재
준비 용품
Hemin 공급 업체
글로벌( 454)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Nanjing Duly Biotech Co.,Ltd | +undefined18013301590 |
melody@njduly.com | China | 2452 | 58 |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
ZhenYiBio Technology Inc | +8615309206328 |
alexxue@zhenyibio.com | China | 299 | 58 |
BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 224 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 |
admin@guyunchem.com | China | 616 | 58 |
Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 524 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 |
2691956269@qq.com | China | 359 | 58 |
Hemin 관련 검색:
프로토폴린 IX 2,5-디메틸피롤 4-펜티노익산 클로로디플루오르메탄 철분
Iron saccharate
PHYTOHEMAGGLUTININ PHA-M
Hematin
Bethanechol
2,3,4,5-TETRAMETHYLPYRROLE
3-BUTEN-1-AMINE
6-Heptenoic acid
Allylamine hydrochloride
4-HEXENOIC ACID
2,4-Dimethylpyrrole
PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN
BOVINE HEMIN
Hemin (Ferriprotoporphyrin IX chloride), min. 95%,HEMIN (FERRIPROTOPORPHYRIN IX CHLORIDE), MIN. 95,Hemin (Ferriprotoporphyrin IX chloride)