DIAMINE OXIDASE

DIAMINE OXIDASE C화학적 특성, 용도, 생산

용도

Diamine Oxidase from porcine kidney has been used in the construction of histamine biosensor.

정의

An enzyme occurring in the animal digestive system; it converts histidine to histamine.

Biological Functions

Diamine oxidase attacks both diamines and histamine in much the same way that MAO attacks monoamines, forming aldehydes. This enzyme is inhibited by carbonyl-blocking reagents and produces hydrogen peroxide, supporting the role of pyridoxal phosphate and the flavin prosthetic groups in the catalytic action of the enzyme. Diamine oxidase is recovered in the supernatant after centrifugation and removal of particulate matter. It is present in kidneys, intestines, liver, lung, and nervous tissue. It limits the biological effects of histamine and the polymethylene amines putrescine and cadaverine. It also attacks monoamines, but at a higher substrate concentration.Plasma amine oxidases are in blood plasma of mammals and include spermine oxidase, which deaminates spermine and other polyamines.

일반 설명

Diamine oxidase from porcine kidney is a homodimer consisting of two equal subunits with a molecular weight of 87 kDa each. Each subunit contains one molecule of pyridoxal phosphate and one atom of copper. The molecular mass of the enzyme is found to be 170 kDa. The enzyme is a glycoprotein containing 5% hexose, 3.3% glucosamine, 2.6% N-acetylglucosamine, and 0.25% N-acetylneuraminic acid. The enzyme exhibits a high affinity for concanavalin A. Optimum pH with cadverine and histamine as substrates is found to be 6.3-7.4.

DIAMINE OXIDASE 준비 용품 및 원자재

원자재

준비 용품

DIAMINE OXIDASE 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58
Hebei Duling International Trade Co. LTD	+8618032673083	sales05@hbduling.cn	China	15745	58
Shaanxi LonierHerb Bio Technology Co Ltd	+86-86-+86-86-029-87551862 +8617702909819	sales006@ingredients-lonier.com	China	2596	58
Nanjing Sunlida Biological Technology Co., Ltd.	025-57798810	sales@sunlidabio.com	China	3750	55
Shanghai Macklin Biochemical Co.,Ltd.	15221275939 15221275939	shenlinxing@macklin.cn	China	15878	55
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Raw material medicin reagent co.,Ltd	025-57798860	sales@njromanme.com	China	4534	58
Guangdong wengjiang Chemical Reagent Co., Ltd.	0751-2815688 13927872512	3007421951@qq.com	China	10084	58
Guangzhou Tomums Life Science Co., Ltd.	020-31155029 18902330969	sales@tomums.cn	China	4698	58

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