Pomalidomide-PEG1-azide
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Pomalidomide-PEG1-azide 속성
- 저장 조건
- 2-8°C
- 용해도
- DMSO : 62.5 mg/mL (156.11 mM; ultrasonic and warming and heat to 60°C)
- 물리적 상태
- Solid
- 색상
- Light yellow to yellow
안전
Pomalidomide-PEG1-azide C화학적 특성, 용도, 생산
용도
Protein degrader builiding block Pomalidomide-PEG1-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.Pomalidomide-PEG1-azide 준비 용품 및 원자재
원자재
준비 용품
Pomalidomide-PEG1-azide 공급 업체
글로벌( 22)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 |
1924344760@confluore.cn | China | 2996 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
Sigma-Aldrich | 021-61415566 800-8193336 |
orderCN@merckgroup.com | China | 51471 | 80 |
Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 |
info@SuperLan-chem.com | China | 9943 | 58 |
Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 |
1924344760@qq.com | China | 4824 | 58 |
Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 |
1927928688@qq.com | China | 1385 | 58 |
Shaanxi borno biotechnology co., LTD | +86-13759708231 |
asherw9@hotmail.com | China | 2351 | 58 |
Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 |
malulu@leyan.com | China | 54986 | 58 |
Xi'an Qiyue Biotechnology Co., Ltd. | 400-400-6966-012-012 17778955912 |
2957605606@qq.com | China | 2535 | 58 |
Pomalidomide-PEG1-azide 관련 검색:
Pomalidomide-PEG3-N3
E3 ligase Ligand-Linker Conjugates 50
Pomalidomide-PEG3-CO2H
Pomalidomide-PEG4-azide
Pomalidomide-PEG2-butyl iodide
E3 Ligase Ligand-Linker Conjugates 22
4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pomalidomide-PEG4-CO2H
E3 Ligase Ligand-Linker Conjugates 1
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG5-CO2H
POMALIDOMIDE-PEG1-CO2H
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG2-N3
Pomalidomide-NH-CO-PEG6-N3
Pomalidomide-PEG5-N3