Anti-LBPA Antibody, clone 6C4

Anti-LBPA Antibody, clone 6C4 구조식 이미지
카스 번호:
상품명:
Anti-LBPA Antibody, clone 6C4
동의어(영문):
Anti-LBPA Antibody, clone 6C4
CBNumber:
CB24816283
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

Anti-LBPA Antibody, clone 6C4 속성

안전

Anti-LBPA Antibody, clone 6C4 C화학적 특성, 용도, 생산

용도

Research Category
Cell Structure

일반 설명

Lyso bis-phosphatidic acid (LBPA, Lysobisphosphatidic acid, L(bis)PA) is a lipid that is exclusively located in late endosomes and is used as a late endosome marker. One of the characteristic features of late endosomes is a complex system of internal membranes within the lumen that contains large amounts of the unique, poorly degradable LBPA, and thus forms a specialized membrane domain within endosomes. Late endosomes function not only as a major protein-sorting compartment, but also an obligatory station for LDL and other endocytosed ligands destined for degradation. Research shows that the LBPA-rich membranes within late endosomes regulate cholesterol transport, presumably by acting as a collection and distribution device. The genetic disease Niemann–Pick type C (NPC) is characterized by both lysosomal and endosomal storage disorders. In skin fibroblasts from NPC patients, cholesterol accumulation is seen within vesicles containing late endosome markers LBPA and Rab7.

Anti-LBPA Antibody, clone 6C4 준비 용품 및 원자재

원자재

준비 용품


Anti-LBPA Antibody, clone 6C4 공급 업체

글로벌( 2)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80

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