로우손

로우손
로우손 구조식 이미지
카스 번호:
83-72-7
한글명:
로우손
동의어(한글):
2-히드록시-1,4-나프토퀴논;로우손;헨나
상품명:
2-Hydroxy-1,4-naphoquinone
동의어(영문):
LAWSONE;2-Hydroxynaphthalene-1,4-dione;2-HYDROXY-1,4-NAPHTHOQUINONE;Lawson;Henna;2-Hydroxynaphthoquinone;3-Hydroxy-1,4-naphthoquinone;Hana;Mendi;Mehendi
CBNumber:
CB2493073
분자식:
C10H6O3
포뮬러 무게:
174.15
MOL 파일:
83-72-7.mol
MSDS 파일:
SDS

로우손 속성

녹는점
192-195 °C (dec.)(lit.)
끓는 점
265.11°C (rough estimate)
밀도
1.2346 (rough estimate)
굴절률
1.5036 (estimate)
저장 조건
Sealed in dry,Room Temperature
용해도
아세토니트릴(약간 용해됨), 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
4.31±0.10(Predicted)
색상 색인 번호
75480
물리적 상태
결정성 분말
색상
노란색
수용성
2g/L(20℃)
Merck
14,5393
BRN
1565260
안정성
안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
InChIKey
CSFWPUWCSPOLJW-UHFFFAOYSA-N
LogP
1.380
CAS 데이터베이스
83-72-7(CAS DataBase Reference)
NIST
1,4-Naphthalenedione, 2-hydroxy-(83-72-7)
EPA
2-Hydroxy-1,4-naphthoquinone (83-72-7)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi,Xn
위험 카페고리 넘버 36/37/38-68-36-22
안전지침서 26-37/39-36/37/39-36
WGK 독일 3
RTECS 번호 QL8200000
TSCA Yes
HS 번호 29146990
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352 피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
2 0

로우손 MSDS


2-Hydroxy-1,4-naphoquinone

로우손 C화학적 특성, 용도, 생산

화학적 성질

Yellow crystal powder

역사

Lawsone (CI Natural Orange 6; CI 75420), also known as henna and isojuglone, occurs in the shrub henna (Lawsone alba). In England, the plant is known as Egyptian privet. The dye was extracted from the leaves of the plant, using sodium bicarbonate, and the extracts used to dye protein fibers an orange shade. Henna is probably the oldest cosmetic known. The ancient Egyptians used it as a hair dye and for staining fingernails. It is said that Mohammed dyed his beard with henna. Lawsone has been identified as 2-hydroxy-1,4-naphthoquinone. It has been synthesized by the Thiele acetylation of 1,4-naphthoquinone followed by hydrolysis and oxidation.

용도

antifungal, sunscreen, antibacterial, antineoplastic

정의

A coloring principle obtained from dried leaves of certain tropical plants (North Africa, India).

일반 설명

Yellow prisms or yellow powder.

공기와 물의 반응

Insoluble in water.

반응 프로필

Phenols, such as 2-Hydroxy-1,4-naphoquinone, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid. Nitrated phenols often explode when heated. Many of them form metal salts that tend toward detonation by rather mild shock.

건강위험

ACUTE/CHRONIC HAZARDS: 2-Hydroxy-1,4-naphoquinone may be absorbed through the skin and can cause skin irritation.

화재위험

Flash point data for 2-Hydroxy-1,4-naphoquinone are not available but 2-Hydroxy-1,4-naphoquinone is probably combustible.

색상 색인 번호

Henna, prepared by powdering the dried leaves of henna plant (Lawsonia inermis L.), is used for coloring and conditioning hair and nails, particularly by Muslims or Hindus. It contains Lawsone, which very rarely induces contact allergy. Most dermatitis caused by “black henna” is due to PPD and derivatives

Purification Methods

Crystallise Lawsone B from *C6H6 or AcOH (m 192.5o, 195-196o). It sublimes in a vacuum (m 194o). It has UV with max at 455nm (aqueous NaOH). [Beilstein 8 H 300, 8 I 635, 8 II 344, 8 III 2543, 8 IV 2360.]

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원자재

준비 용품


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