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Ceforanide

Ceforanide 구조식 이미지

카스 번호:: 60925-61-3

상품명:: Ceforanide

동의어(영문):: C06884;BL-S-786;Ceforanide;CEFORANIDE (200 MG);Antibiotic BL-S-786;Ceforanide USP/EP/BP;Ceforanide (1097807);2-(2,4-Dimethylphenyl)sulf;Bacterial,inhibit,Antibiotic,Inhibitor,Ceforanide;(6R,7R)-7-(2-(2-(Aminomethyl)phenyl)acetamido)-3-(((1-(carboxymethyl)-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

CBNumber:: CB2501637

분자식:: C20H21N7O6S2

포뮬러 무게:: 519.55

MOL 파일:: 60925-61-3.mol

속성

안전

용도

공급 업체 85

Ceforanide 속성

녹는점: >150° (dec)

밀도: 1.79±0.1 g/cm3(Predicted)

저장 조건: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

용해도: 알칼리성 용액(약간), DMSO(약간, 가온), 메탄올(약간)에 용해됨

산도 계수 (pKa): 2.52±0.10(Predicted)

물리적 상태: 고체

물리적 상태: 단단한 모양

색상: 흰색에서 옅은 갈색까지

안정성: 흡습성

InChIKey: SLAYUXIURFNXPG-CRAIPNDOSA-N

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

HS 번호	2941906000
기존화학 물질	KE-01465

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	그림 문자	P- 코드
H317	알레르기성 피부 반응을 일으킬 수 있음	피부 과민성 물질	구분 1	경고		P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H334	흡입 시 알레르기성 반응, 천식 또는 호흡 곤란 등을 일으킬 수 있음	호흡기 과민성 물질	구분 1	위험		P261, P285, P304+P341, P342+P311,P501

예방조치문구:

P261	분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P284	호흡 보호구를 착용하시오.
P304+P340	흡입하면 신선한 공기가 있는 곳으로 옮기고 호흡하기 쉬운 자세로 안정을 취하시오.
P342+P311	호흡기 증상이 나타나면 의료기관(의사)의 진찰을 받으시오.

Ceforanide C화학적 특성, 용도, 생산

개요

Ceforanide is a second generation cephalosporin with good β-lactamase resistance. It has a serum half-life of about three hours, allowing twice-daily dosing.

용도

Ceforanide is a cephalosporin based antibiotic used in the sterilization in various medical procedures.

정의

ChEBI: A second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many col forms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Ari ona species.

Antimicrobial activity

A semisynthetic parenteral cephalosporin with activity broadly similar to that of cefalotin. Its activity in vitro is significantly reduced in the presence of serum. A 1 g intravenous dose achieves a concentration of c. 135 mg/L at the end of infusion. The response after 0.25, 0.5 and 1 g intravenous doses is essentially linear. A 1 g intramuscular dose produces mean peak values of around 70 mg/L. Plasma protein binding is around 85%.
It is almost entirely eliminated in the urine with a halflife of about 2.5 h, 80–95% being recovered in the first 12 h. The half-life is inversely related to renal function, rising to around 20 h when the creatinine clearance falls below 5 mL/min. About half the dose is removed by hemodialysis over 6 h.
It is generally well tolerated; phlebitis and pain at the site of injection are reported in some patients with occasional transient neutropenia and increased transaminase levels. It has been used principally for the treatment of infections due to Gram-positive cocci, including staphylococcal and streptococcal soft-tissue infections, but is no longer widely available.

Ceforanide 준비 용품 및 원자재

원자재

준비 용품

Ceforanide 공급 업체

글로벌( 85)공급 업체

공급자	전화	이메일	국가	제품 수	이점
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9553	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9821	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58

Ceforanide 관련 검색:

아세틸 염화물 아세트아미노펜 2,4-펜탄디온 아세틸 보조 효소 A 페닐초산 PHENYL VALERATE 2-(5-Mercaptotetrazole-1-yl)ethanol 1H-Tetrazole-1-acetic acid 7-TMCA 7-Phenyl-acetamido-deacetoxy-cephalosporanic-acid 1-Ethyl-1H-1,2,3,4-tetrazole-5-thiol 2-aminomethylphenylacetic acid (intermediate of ceforanide) 5-Mercapto-1H-tetrazole-1-acetic acid 1-ETHYL-1H-TETRAZOLE Ceforanide Acetyl-resveratrol ACETAMINOPHENOL BP/USP 1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl-