소듐 타우로데옥시콜레이트 수화물
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소듐 타우로데옥시콜레이트 수화물 속성
- 녹는점
- 168 °C (dec.)(lit.)
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- H2O: 용해성0.5M, 투명, 무색~엷은 노란색
- 물리적 상태
- 결정성 고체
- BRN
- 3901204
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
---|---|---|---|
HS 번호 | 29242998 |
소듐 타우로데옥시콜레이트 수화물 C화학적 특성, 용도, 생산
개요
Sodium taurodeoxycholate hydrate is a bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. It has also been used in a study to investigate polymorphic behavior in protein surfactant mixtures.Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.
용도
A hydrate form of sodium taurodeoxycholate (T009005), a steroid which rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.일반 설명
Sodium tauroursodeoxycholate is a bile salt which is naturally present in the small bowel.Purification Methods
The Na salt is dissolved in the smallest volume of H2O, a saturated solution of aqueous NaCl/Et2O is added and the mixture is stored at 0o for 24hours. Then shake the mixture well, keep it in the cold for another day and filter the crystals with gentle shaking, wash them with ice-cold saturated aqueous NaCl saturated with Et2O, dry them over CaCl2 and extract them with absolute EtOH. Add ~10mL of H2O to the solid followed by enough Et2O to incipient cloudiness. Store it overnight at 0o. Add ice-cold Et2O to make 250mL, collect the crystals, wash them with Et2O then pet ether and dry them in air. The purification can be repeated with NaCl and Et2O with ~85% recovery. NB: precipitation will not occur unless enough H2O is present. Its solubility in H2O is 10%. [Cortese J Am Chem Soc 59 2532 1937.] The free acid has m 141-144o. [Norman Ark Kemi 8 331 1956.] It forms mixed micelles and solubilises some membrane proteins [Hajjar et al. J Biol Chem 2 5 8 192 1983]. [Beilstein 10 IV 1611.]소듐 타우로데옥시콜레이트 수화물 준비 용품 및 원자재
원자재
준비 용품
소듐 타우로데옥시콜레이트 수화물 공급 업체
글로벌( 143)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5909 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 |
ada@ipurechemical.com | CHINA | 3465 | 58 |
Wuhan Fortuna Chemical Co., Ltd | +86-27-59207850 +86-13986145403 |
info@fortunachem.com | China | 5986 | 58 |
소듐 타우로데옥시콜레이트 수화물 관련 검색:
나트륨 콜산염 염소 산
Taurohyodeoxycholic acid sodium salt hydrate
Taurodeoxycholic acid sodium salt
taurohyodeoxycholic acid
Sodium taurocholate
TAUROHYODEOXYCHOLIC ACID SODIUM SALT
TAUROCHOLIC ACID SODIUM SALT HYDRATE
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
SODIUM GLYCOCHOLATE HYDRATE, 98
Sodium glycocholate hydrate
Glycochenodeoxycholic acid sodium salt
Tauroursodeoxycholic acid
Ursodeoxycholic acid
Sodium tauroglycocholate
Deoxycholic acid