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CYTOCHALASIN D

CYTOCHALASIN D 구조식 이미지
카스 번호:
22144-77-0
상품명:
CYTOCHALASIN D
동의어(영문):
Nsc209835;ZYGOSPORIN A;Lygosporin a;CYTOCHALACIND;CYTOCHALICIND;Cytohalasin d;CYTOCHALASIN D;19-trien-17-one;CYTOCHALASIN D(RG);InSolution? Cytochalasin D,
CBNumber:
CB2672937
분자식:
C30H37NO6
포뮬러 무게:
507.62
MOL 파일:
22144-77-0.mol

CYTOCHALASIN D 속성

녹는점
255-260°C
끓는 점
595.84°C (rough estimate)
밀도
1.1764 (rough estimate)
굴절률
1.6310 (estimate)
인화점
87℃
저장 조건
−20°C
용해도
DMSO: soluble
물리적 상태
White solid
산도 계수 (pKa)
11.95±0.70(Predicted)
BRN
1632828
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 25-63
안전지침서 36/37-45
유엔번호(UN No.) UN 1544 6.1/PG 2
WGK 독일 3
RTECS 번호 GZ4850000
위험 등급 6.1(a)
포장분류 I
HS 번호 29337900
그림문자(GHS):
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H300 삼키면 치명적임 급성 독성 물질 - 경구 구분 1,2 위험 P264, P270, P301+P310, P321, P330,P405, P501
H361 태아 또는 생식능력에 손상을 일으킬 것으로 의심됨 생식독성 물질 구분 2 경고 P201, P202, P281, P308+P313, P405,P501
예방조치문구:
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P281 요구되는 개인 보호구를 착용하시오
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.

CYTOCHALASIN D C화학적 특성, 용도, 생산

화학적 성질

Powder

용도

Cytochalasin D acts as an anti-hypertensive drug acting on human intestinal epithelial caco-2 cells. Also has activity in HMG-CoA reductase inhibitors used in the lowering of cholesterol. Actin inhib itor, actin polymerization inhibitor affecting cell movement, growth, phagocytosis and even secretion.

용도

Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumour agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.

용도

Cytochalasin D is the most studied of the cytochalasins. Like most of the members of this mycotoxin class, cytochalasin D exhibits potent inhibition of actin filament function leading to cell death by apoptosis. This led to early investigation of the metabolite as an antitumor agent. Cytochalasin D has become one of the standard cellular probes for investigating the role of actin in cell biology.

용도

A cell cycle arresting compound used in actin polymerization studies and cytological research

정의

ChEBI: An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis.

일반 설명

Needles or fluffy white powder.

반응 프로필

CYTOCHALASIN D may be sensitive to exposure to heat. CYTOCHALASIN D can react with strong oxidizing agents, strong acids and strong bases. .

화재위험

Flash point data for CYTOCHALASIN D are not available; however, CYTOCHALASIN D is probably combustible.

생물학적 활성

Potent disruptor of actin filament function. Alters tight junction permeability. Unlike cytochalasin B, does not inhibit monosaccharide transport across the plasma membrane.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

CYTOCHALASIN D 준비 용품 및 원자재

원자재

준비 용품


CYTOCHALASIN D 공급 업체

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