DECANOIC-2,2-D2 ACID

DECANOIC-2,2-D2 ACID C화학적 특성, 용도, 생산

개요

Decanoic acid-d₂ is intended for use as an internal standard for the quantification of decanoic acid by GC- or LC-MS. Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC₅₀ = 0.52 mM) over those expressing GluA1 (IC₅₀ = 2.09 mM) or GluA1 and GluA2 subunits (IC₅₀ = 1.16 mM). It inhibits epileptiform activity induced by pentylenetetrazole or low magnesium in rat hippocampal slices. Decanoic acid (1 mM) induces contractions in isolated guinea pig duodenum, an effect that can be blocked by the muscarinic acetylcholine receptor antagonist hyoscine, voltage-gated sodium channel inhibitor tetrodotoxin (Item Nos. 14964 | 14963), or M₂ muscarinic acetylcholine receptor antagonist hexamethonium . It increases the escape threshold in an orofacial mechanical stimulation test in rats when administered at a topical dose of 30% in ointment form, indicating analgesic activity. This effect can be blocked by the muscarinic acetylcholine receptor antagonist methoctramine . Plasma levels of decanoic acid are increased in patients with colorectal cancer when compared to patients with breast cancer or ulcerative colitis or without cancer.

용도

Decanoic-2,2-d2 Acid (CAS# 62716-49-8) is a useful isotopically labeled research compound.

DECANOIC-2,2-D2 ACID 준비 용품 및 원자재

원자재

준비 용품

DECANOIC-2,2-D2 ACID 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Clearsynth Labs Limited	+91-22-26355700	info@clearsynth.com	India	9685	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Nanjing Haolv Biotechnology Co.,Ltd	025-84622273 02584622273;	kexin.zhou@haolvbiotech.com	China	3021	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Shanghai Yufei Pharmaceutical Technology Co., Ltd.	+8618221552033	edward-atom@hotmail.com	CHINA	876	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
ChengDu SinoStandards Bio-Tech Co.,Ltd. ，	028-83243028 19136088901	sinostandards@163.com	China	5044	58
Manhag Testing Technology Co., Ltd	020-020-3846236 17688849268	2443244976@qq.com	China	7775	58
Yancheng Tongming Biotechnology Co., Ltd.	15195160625	2863565288@qq.com	China	5194	58
Changzhou Bojia Biomedical Technology Co., Ltd.	2122619822	czbjpharma@126.com	China	18488	58

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