클로로탄산 페닐에스테르
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클로로탄산 페닐에스테르 속성
- 녹는점
- -28 °C
- 끓는 점
- 74-75 °C/13 mmHg (lit.)
- 밀도
- 1.248 g/mL at 25 °C (lit.)
- 증기 밀도
- 1 (vs air)
- 증기압
- 1.22 psi ( 20 °C)
- 굴절률
- n
20/D 1.511(lit.)
- 인화점
- 168 °F
- 저장 조건
- 2-8°C
- 용해도
- N,N-디메틸포름아미드와 혼합 가능.
- 물리적 상태
- 액체
- 색상
- 투명한
- 수용성
- 가수 분해
- 감도
- Moisture Sensitive
- BRN
- 606778
- CAS 데이터베이스
- 1885-14-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T+ | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-26-34-41-38-29-37 | ||
| 안전지침서 | 26-28-36/37/39-45-28A | ||
| 유엔번호(UN No.) | UN 2746 6.1/PG 2 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | FG3850000 | ||
| F 고인화성물질 | 10-19-21 | ||
| 자연 발화 온도 | 540 °C | ||
| TSCA | Yes | ||
| 위험 등급 | 6.1 | ||
| 포장분류 | II | ||
| HS 번호 | 29159020 | ||
| 독성 | LD50 orally in Rabbit: 1730 mg/kg LD50 dermal Rabbit 4880 mg/kg | ||
| 기존화학 물질 | 97-3-86 |
클로로탄산 페닐에스테르 C화학적 특성, 용도, 생산
화학적 성질
clear oily liquid. Corrosive. Insoluble in water, soluble in ethanol, ether, easily soluble in petroleum ether.용도
Phenyl chloroformate is used in the synthesis of poly(2-(phenoxycarbonyloxy)ethyl methacrylate) and phenyl-(4-vinylphenyl) carbonate. It acts as a precursor of phenyl mixed anhydrides which are used in peptide coupling reactions. It serves as a dehydrating reagent for the conversion of primary amides to nitriles and an intermediate in the synthesis of pharmaceuticals and carbamates.제조 방법
Phenyl chloroformate is synthesized by the reaction of phenol with phosgene. Phenol was dissolved in chloroform, phosgene was introduced under cooling, and the absorbed phosgene was in an equal molar ratio to phenol, and equimolar N,N-dimethylaniline was added dropwise under stirring at 5-10 °C. Then add cold water to dilute, separate the oil layer, wash with dilute hydrochloric acid and water successively. After drying with anhydrous calcium chloride, chloroform is evaporated, and then distilled under reduced pressure to collect 74-75°C (1.73kPa) fraction, which is phenyl chloroformate. The yield is about 90%.일반 설명
Phenyl chloroformate appears as a colorless liquid with a strong odor. Toxic by ingestion, inhalation and skin absorption. Very irritating to skin and eyes. Used as a reagent for organic synthesis.공기와 물의 반응
Emits fumes containing HCl in moist air. Decomposes in water to form HCl.반응 프로필
Phenyl chloroformate is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].건강위험
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.화재위험
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.Safety Profile
Poison by inhalation. Moderately toxic by ingestion and skin contact. A corrosive sktn and eye irritant. See also ESTERS. When heated to decomposition it emits toxic fumes of Cl-.클로로탄산 페닐에스테르 준비 용품 및 원자재
원자재
준비 용품
Xamoterol hemifumarate
Rilmenidine
camazepam
5-BROMO-2(3H)-BENZOXAZOLONE
1,4-Benzenedimethanol
ethyl phenyl carbonate
Leuprorelin
2-Piperidineethanol
BENZYL 3-PYRROLINE-1-CARBOXYLATE
Cbz-D-Phenylalaninol
4,6-Dimethoxy-2-(phenoxycarbonyl)aminopyrimidine
Phenyl carbamate
BENZYL PHENYL CARBONATE 97
CarbaMic acid, bis(2-chloroethyl)-, phenyl ester
클로로탄산 페닐에스테르 공급 업체
글로벌( 379)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Zouping mingyuan import & export trading co., ltd | +86-0543-2240078 +8618364991597 |
myzhao793@163.com | China | 994 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12457 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |