(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터
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(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터 속성
- 녹는점
- -5,5°C
- 끓는 점
- 235-240 °C18 mm Hg(lit.)
- 밀도
- 0.91 g/mL(lit.)
- 굴절률
- n
20/D 1.470
- 인화점
- 330 °C
- 저장 조건
- -20°C
- 용해도
- 클로로포름: 0.1 g/mL, 투명, 무색
- 물리적 상태
- 액체
- 색상
- 맑은 연한 노란색
- Merck
- 14,9732
- BRN
- 1718692
- Dielectric constant
- 3.2(26℃)
- 안정성
- 안정성 안정적이지만 공기와 빛에 민감합니다. 강한 산화제와 호환되지 않습니다.
- LogP
- 23.444 (est)
- CAS 데이터베이스
- 122-32-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 11-20/21/22-53 | ||
안전지침서 | 24/25-39-26 | ||
유엔번호(UN No.) | UN 1282 3/PG 2 | ||
WGK 독일 | - | ||
RTECS 번호 | RG1936500 | ||
F 고인화성물질 | 10-23 | ||
TSCA | Yes | ||
HS 번호 | 29161500 | ||
유해 물질 데이터 | 122-32-7(Hazardous Substances Data) | ||
기존화학 물질 | KE-26511 |
(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터 C화학적 특성, 용도, 생산
개요
1,2,3-Trioleoyl glycerol is a triacylglycerol that contains oleic acid (Item Nos. 90260 | 24659) at the sn-1, sn-2, and sn-3 positions. It inhibits oxidized LDL-induced decreases in cell viability and superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities and increases in apoptosis in endothelial cells when used at a concentration of 10 μM. 1,2,3-Trioleoyl glycerol has been found in sunflower, corn, and extra virgin olive oils. It has been used as a standard for the quantification of triacylglycerols in extra virgin olive oil by high temperature gas chromatography-(ionic trap)mass spectrometry (HTGC-(IT)MS). 1,2,3-Trioleoyl glycerol is a major component of Lorenzo''s oil.화학적 성질
Triolein occurs as a clear, colorless to yellowish oily liquid, and is tasteless and odorless.용도
Glycerol trioleate can be used as an emulsifier, also as creams, lotions and lipsticks matrix. Used as textile finishing agent in textile industry, also used as additive in pigment grind. In pharm industry, used as ointment, emulsifiable paste, suppository, lotion, emulsifier in air agent, stabilizing agent, lubricating agent, antifoaming agents. In food industry, it has the function as emulsify, disperse, defoaming, blister, antistaling of starch and control fat agglutination, usually used as agent in candy, ice cream, cookie and bread. When used in beverage, could avoid ester to float, and avoid protein to sink, therefore to improve stability. When used in bread, cookie , could improve organization structure, increase volume, antistaling, prolong warranty validity.정의
ChEBI: A triglyceride formed by esterification of the three hydroxy groups of glycerol with oleic acid. Triolein is one of the two components of Lorenzo's oil.생산 방법
Triolein is manufactured by the esterification of fractionated fatty acids, mainly oleic acid and glycerin.일반 설명
Glyceryl trioleate is derived from glycerol. It is composed of three oleic acid units and is an unsaturated triglyceride.Pharmaceutical Applications
Triolein is used as a solubilizer and solvent in injectable preparations. It has been used in marketed preparations of sustained-release injections of cytarabine and multivesicular liposomal injections of morphine sulfate. It has also been used in enteric coatings for oral preparations in combination with other enteric coating excipients to protect against degradation by pancreatic lipase.Triolen is used in personal care products as a skin-conditioning and viscosity-controlling agent.
Safety
Triolein is used in injectable preparations, in enteric coatings for oral preparations, and in personal care products. Chronic exposure may cause nausea and vomiting, and higher exposures may cause unconsciousness.The Cosmetic Ingredient Review (CIR) Expert Panel found that dermal application of triolein was not associated with significant irritation, and no evidence of sensitization or photosensitization was observed. Ocular exposures were found to be only mildly irritating to eyes. Triolein has not been found to be genotoxic in a number of in vitro and in vitro assay systems. Subcutaneous injections of triolein in rats showed no tumors at the injection site. The CIR Expert Panel also noted that metabolism data indicated that glyceryl triesters (including triolein) followed the same metabolic pathways as fats in food. They were split into monoglycerides, free fatty acids, and glycerol, all of which were absorbed into the intestinal mucosa and metabolized further. Therefore, oral exposure to these compounds was not found to be a concern.
A triolein-based amphotericin emulsion showed better safety with a higher LD50 in rats as compared with the conventional amphotericin deoxycholate.
저장
Triolein is classified as a stable compound but is sensitive to air and light. It should be stored in tightly sealed containers in a dry area at 2–8℃. Thermal decomposition of triolein may lead to release of irritating gases and vapors such as carbon oxides. Exposure to air and moisture over prolonged periods should be avoided.비 호환성
Triolein is incompatible with strong oxidizing agents and spontaneously flammable products. Being a triglyceride ester, triolein can be hydrolyzed by strong acids, and particularly by strong bases. It is possible for primary amines to form an adduct across the olefinic double bonds (analogous to a Michael addition).Regulatory Status
Included in the FDA Inactive Ingredients Database (liposomal suspension for epidural injections). Included in parenteral medicines (suspension for intrathecal injection) licensed in the UK.Triolein is included in the CIR category as safe for use in cosmetics and personal care products. Its use as an indirect food additive has been approved by the FDA.
(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터 준비 용품 및 원자재
원자재
준비 용품
(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터 공급 업체
글로벌( 434)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7534 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
City Chemical LLC | 2039322489 |
sales@citychemical.com | United States | 168 | 58 |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
(Z)-9-옥타데센산 1,2,3-프로판트라일 에스터 관련 검색:
글리세린 염화 2,3,5-트리페닐 테트라졸륨 (Z)-9-옥타데센산 1,2,3-프로판트라일 에스터
Glycerol tristearate
DL-GLYCERIC ACID
GLYCEROL TRIACETYLRICINOLEATE
Triolein-carboxyl-13c399atom%13c,triolein-carboxyls-13c3,TRIOLEIN-CARBOXYL-13C3,TRIOLEIN (1,1,1-13C3)
TRIOLEIN, [GLYCEROL-1,2,3-3H]
D-glucitol hexaoleate
TRIOLEIN-GLYCERYL-13C3
TRIOLEIN, [9,10-3H(N)]
TRIOLEIN PEG-6 ESTERS
PEG-25 GLYCERYL TRIOLEATE
PEG-15 GLYCERYL TRIOLEATE
EMERY
TRIOLEIN (CAS#: 122-32-7) 1X2ML
Triolein (-1-13C)
Triolein (-14,14,15,15,17,18-D6)