ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 구조식 이미지
카스 번호:
상품명:
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN
동의어(영문):
Anti-HnRNP-L;Anti-P/OKcl.14;ANTI-HNRNP M1-M4;MONOCLONAL ANTI-HNRNP-L;MONOCLONAL ANTI-HNRNP-Q;MONOCLONAL ANTI-HNRNP M1-M4;MONOCLONAL ANTI-HNRNP-A2/B1;Anti-HNRPL antibody produced in rabbit;ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN;Anti-HNRPL (AB2) antibody produced in rabbit
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN C화학적 특성, 용도, 생산
용도
Monoclonal Anti-hnRNP-A2/B1 antibody produced in mouse been used in :
enzyme linked immunosorbent assay (ELISA)
immunoblotting
immunoprecipitation
immunocytochemistry
일반 설명
This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. (provided by RefSeq)
Biochem/physiol Actions
In cells, it actively participates in pre-messenger RNA (pre-mRNA) processing, mRNA metabolism and transportation. It is overexpressed in the initial stage of lung cancer and in premalignant lesions. It also participates in neurodegeneration mediated by rCGG (repeats).
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 준비 용품 및 원자재
원자재
준비 용품
ANTI-HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 공급 업체
