디페닐아세토니트릴
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디페닐아세토니트릴 속성
- 녹는점
- 71-73 °C (lit.)
- 끓는 점
- 181 °C/12 mmHg (lit.)
- 밀도
- 1.1061 (rough estimate)
- 증기압
- 21.3 hPa (190 °C)
- 굴절률
- 1.5850 (estimate)
- 인화점
- 120 °C
- 저장 조건
- Store below +30°C.
- 용해도
- INSOLUBLE
- 물리적 상태
- Crystalline Powder
- 색상
- White to creamy or faint yellow
- 수용성
- INSOLUBLE
- Merck
- 14,3316
- BRN
- 1911160
- InChIKey
- NEBPTMCRLHKPOB-UHFFFAOYSA-N
- CAS 데이터베이스
- 86-29-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36-37/39 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | AL9800000 | ||
| TSCA | Yes | ||
| HS 번호 | 29269095 | ||
| 독성 | LD50 orally in Rabbit: 3500 mg/kg |
디페닐아세토니트릴 C화학적 특성, 용도, 생산
화학적 성질
Diphenylacetonitrile is a white to creamy or faint yellow crystalline powder, Soluble in ethanol, ether. It is obtained by bromination and condensation of phenylacetonitrile.Diphenylacetonitrile is mainly used as an intermediate to manufacture API which deals in treatment of respiratory stimulant. It is used to manufacture APIs like stomach amine, Aminepentamide Sulphate, Diphenoxylate, Diphenylacetaldehyde, Doxapram, Loperamide, Methadone.용도
Mathadone (M225865) impurity. Used in synthesis of methadone, antispasmodics and other pharmaceuticals.Diphenylacetonitrile is used to synthesize isocyanate, which is further prepared into UV paint, PU paint, transparent elastomer and adhesive, etc. In addition, it is also used in polyamide and epoxy resin industries.
제조 방법
Diphenylacetonitrile can be prepared in good yield by the dehydration of the amide of diphenyl acetic acid with phosphorous oxychloride. Diphenylacetonitrile undergoes anhydrous condensation with ethyl-4-bromo-butyrate. This is followed by its hydrolysis in alkaline medium that is used in the quantitative determination of 3-cyano-3,3-diphenylpropionic acid.일반 설명
Diphenylacetonitrile can be prepared in good yield by the dehydration of the amide of diphenyl acetic acid with phosphorous oxychloride.
Safety Profile
Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. Questionable carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits toxic fumes of NOx, and CN-. See also NITRILES.Purification Methods
Crystallise the nitrile from EtOH or pet ether (b 90-100o). [Beilstein 9 H 674, 9 IV 2505.]디페닐아세토니트릴 준비 용품 및 원자재
원자재
준비 용품
4-BROMO-2,2-DIPHENYLBUTYRONITRILE
다이페녹시레이트
독사프람
DIPHENYLACETALDEHYDE
Loperamide
메타돈하이드로클로라이드
디메바미드
3,3-Diphenyltetrahydrofuran-2-ylidene(dimethyl)ammonium bromide
다이파이파논
Proadifen
디페닐아세토니트릴 공급 업체
글로벌( 407)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Yixing Beiqi Biotechnology Co., Ltd | +undefined13771333006 |
1127389307@qq.com | China | 2 | 58 |
| Hebei Binshare New Material Co. Ltd | +8615175385372 |
china03@hbbinshare.com | China | 105 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | 15013857715 |
admin@nexconn.com | CHINA | 3004 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 23035 | 58 |
| Hanhong Medicine Technology (Hubei) Co., Ltd. | 027-86832068 +8618162639991 |
parr@hanhong-api.com | China | 200 | 58 |
| Baoji Guokang Healthchem co.,ltd | +8615604608665 15604608665 |
dominicguo@gk-bio.com | CHINA | 9457 | 58 |
| Zhuozhou Wenxi import and Export Co., Ltd | +8613111626072 |
zzwenxi@126.com | CHINA | 13187 | 58 |
| Shandong Zhishang New Material Co., Ltd. | +8617653113209 |
sales002@sdzschem.com | China | 3056 | 58 |
| ZHEJIANG ESTCHEM CO.,LTD | 15957180504 |
sales@zjestchem.com | China | 185 | 58 |
| Wuhan wingroup Pharmaceutical Co., Ltd | +8613296627870 |
admin@whwingroup.com | China | 792 | 58 |
디페닐아세토니트릴 관련 검색:
페닐아세토나이트릴 비벤질 디페닐아세토니트릴 벤질
2-[CYANO(4-FLUOROPHENYL)METHYL]BENZENECARBONITRILE
(4-AMINOPHENYL)PHENYLACETONITRILE HYDROCHLORIDE,97%
GAMMA-CHLORO-ALPHA,ALPHA-DIPHENYL-BETA-METHYLBUTYRONITRILE
2-CHLORO-6-[CYANO(4-FLUOROPHENYL)METHYL]BENZENECARBONITRILE
2-[(2-CHLORO-6-FLUOROPHENYL)(CYANO)METHYL]-6-FLUOROBENZENECARBONITRILE
2-[CYANO(PHENYL)METHYL]-6-FLUOROBENZENECARBONITRILE
2-(4-fluorophenyl)-2-phenyl-acetonitrile
DIPHENOXYLATE HYDROCHLORIDE
2-[(4-CHLOROPHENYL)(CYANO)METHYL]BENZENECARBONITRILE
4-AMINO-2-CHLORODIPHENYLACETONITRILE
1,2-DI[4-(1-CYANO-1-PHENYLPROPYL)PHENYL]DIAZ-1-EN-1-IUM-1-OLATE
(4-[CYANO(DIPHENYL)METHYL]PHENYL)(DIPHENYLMETHYLIDENE)AMMONIUMOLATE
2,2-Diphenylpropionitrile
2-[CYANO(4-FLUOROPHENYL)METHYL]-6-FLUOROBENZENECARBONITRILE