트리 메틸 포스페이트
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트리 메틸 포스페이트 속성
- 녹는점
- -46 °C (lit.)
- 끓는 점
- 197 °C (lit.)
- 밀도
- 1.197 g/mL at 25 °C (lit.)
- 증기압
- 1.133 hPa (25 °C)
- 굴절률
- n
20/D 1.395(lit.)
- 인화점
- 107 °C
- 저장 조건
- Store below +30°C.
- 용해도
- 1000g/L
- 물리적 상태
- 액체
- 색상
- 투명한
- Specific Gravity
- 1.197
- 수용성
- 500G/L(25℃)
- 감도
- Moisture Sensitive
- BRN
- 1071731
- Dielectric constant
- 21.260000000000002
- InChIKey
- WVLBCYQITXONBZ-UHFFFAOYSA-N
- LogP
- -0.46 at 25℃
- CAS 데이터베이스
- 512-56-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T,Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 46-22-40-68-45-20/21/22-38-36 | ||
안전지침서 | 53-36/37-45-36/37/39-26 | ||
유엔번호(UN No.) | 2810 | ||
WGK 독일 | 1 | ||
RTECS 번호 | TC8225000 | ||
F 고인화성물질 | 21 | ||
위험 참고 사항 | Toxic/Moisture Sensitive | ||
TSCA | Yes | ||
HS 번호 | 2919 90 00 | ||
유해 물질 데이터 | 512-56-1(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 840 mg/kg LD50 dermal Rabbit 3388 mg/kg | ||
기존화학 물질 | KE-28647 |
트리 메틸 포스페이트 C화학적 특성, 용도, 생산
화학적 성질
Trimethyl phosphate (TMP), the simplest trialkyl ester of phosphoric acid, It is a colourless, nonvolatile liquid. soluble in most organic solvents, low solubility in water. TMP is stable in neutral, acidic or alkaline solutions, and is classified as "not readily biodegradable". Direct photodegradation is not expected because trimethyl phosphate does not absorb UV light.용도
Trimethyl phosphate is used as an intermediate in organic synthesis. Its industrial applications are much fewer than those of other organic phosphates.Trimethyl phosphate undergoes hydrolysis in contact with water, so it should be stored in a moisture-proof manner. Due to its hydrolysis and release of PO43-, thus becoming a homogeneous precipitant for the formation of insoluble phosphate precipitation, often used as a precipitation reagent for zirconium and hafnium and as a diffusion source for the determination of semiconductors. In addition, trimethyl phosphate is also a phospholipid extractant for the extraction and separation of certain metal ions.생산 방법
Trimethyl phosphate is prepared by treating phosphorus oxychloride with methanol in the presence of an amine base:POCl3 + 3 CH3OH + 3 R3N → PO(OCH3)3 + 3 R3NH+Cl
It is a tetrahedral molecule that is a weakly polar solvent.
정의
ChEBI: Trimethyl phosphate is a trialkyl phosphate that is the trimethyl ester of phosphoric acid. It has a role as an insect attractant.일반 설명
Trimethyl phosphate appears as a pale straw colored liquid. Inhalation may irritate respiratory tract. Vapor or liquid may irritate skin or eyes. Ingestion may irritate the mucous membranes of the gastrointestinal tract.반응 프로필
TRIMETHYL PHOSPHATE may explode when heated. Residue from a large scale atmospheric pressure distillation of Trimethyl phosphate has exploded violently. Trimethyl phosphate is incompatible with nitrates. . Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.위험도
Toxic by ingestion and inhalation, strong irritant to skin and eyes. trimethyl phosphate (TMP) is absorbed rapidly and completely by inhalation of its vapour, through the skin and by ingestion (WHO).화재위험
Trimethyl phosphate is nonflammable.공업 용도
1 Gasoline additive at 0.25 g/gal for controlling surface ignition and spark plug fouling.2 Methylating agent, chemical intermediate in the production of polymethyl polyphosphates.
3 Flame retardant solvent for paints and polymers.
4 Catalyst in the preparation of polymers and resins.
Safety Profile
Suspected carcinogen with experimental carcinogenic, neoplastigenic, tumorigenic, and teratogenic data. Moderately toxic by ingestion, skin contact, intraperitoneal, and intravenous routes. Experimental reproductive effects. Human mutation data reported. Explodes when heat distilled. When heated to decomposition it emits toxic fumes of POx. See also ESTERS.신진 대사
A system utilizing isolated anterior forearm stratum corneum conjunctum of man to study skin penetrating capacity of a series of organic phosphates was developed. Trimethyl phosphate was tested in the system and had the greatest skin-penetrating capacity of the 8 related compounds tested (Marzulli et al 1965).Rats treated orally at 100 mg/kg and mice treated i.p. at 1000 mg/kg with [32]P-labeled trimethyl phosphate excreted primarily dimethyl phosphate in the urine. Only traces of the parent compound were detected, and only in the rats at less than 6 h after treatment. S-Methyl cysteine and S-methyl cysteine N-acetate were also isolated. Small amounts of S-methyl glutathione were detected, presumably the initial methylation product in this series of metabolites (Jones 1970). Metabolism of trimethyl phosphate was faster in the mouse than in the rat, but there was no evidence of further conversion to monomethyl phosphate or inorganic phosphate in either species (Jackson and Jones 1968).
Purification Methods
Purify the phosphate by fractionation through an efficient column at high reflux ratio. It is quite soluble in H2O; the solubility is 1:1 at 25o. [Becker J Am Chem Soc 74 2923 1952, IR: Bergmann et al. J Chem Soc 847 1952, McIvor et al. Can J Chem 36 820 1958, Kosolapoff Organophosphorus Compounds, Wiley p 258 1950, and Cherbuliez in Organo Phosphorus Compounds (Kosolapoff & Maier eds) Wiley Vol 6 pp 211-577 1973, Beilstein 1 IV 1259.]폐기물 처리
TMP is mixed with a combustible solvent and destroyed by burning in a chemical incinerator.트리 메틸 포스페이트 준비 용품 및 원자재
원자재
포스포러스옥시클로라이드
메틸알콜
TETRAMETHYLPYROPHOSPHATE
모노메틸 인산염
TRIMETHYL THIOPHOSPHATE
이소퀴놀린 N-옥사이드
DIMETHYLPHOSPHINE OXIDE
메틸인산디메틸에스테르
트리메틸포스파이트
FENCHLORPHOS-OXON
준비 용품
트리 메틸 포스페이트 공급 업체
글로벌( 454)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Zhangjiagang Xinya Chemical Co., Ltd. | +86-512-58980899 +8613915696858 |
sales@zjgxinyachem.com | China | 44 | 58 |
Kindchem(Nanjing)Co.,Ltd | +86-025-025-85281586 +8618651653755 |
sales@kindchem.cn | China | 1227 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7613 | 58 |
Shandong Juchuang Chemical Co., LTD | +86-18885615001 +86-18885615001 |
admin@juchuangchem.com | China | 387 | 58 |
airuikechemical co., ltd. | +undefined86-15315557071 |
sales02@airuikechemical.com | China | 994 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 |
info@tnjchem.com | China | 2989 | 55 |
Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |