N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄
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N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄 속성
- 녹는점
- 199℃ (Decomposition)
- 밀도
- 1.2711 (estimate)
- 저장 조건
- Store at -20°C
- 용해도
- DMSO: 250 mg/mL (520.37 mM)
- 수용성
- 물에 거의 녹지 않음
- 물리적 상태
- powder to crystal
- 색상
- 흰색에서 거의 흰색
- Merck
- 14,5202
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | BP0693200 | ||
| HS 번호 | 2924296000 | ||
| 독성 | LD50 oral in rat: > 10gm/kg |
N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄 C화학적 특성, 용도, 생산
용도
Isopropamide Iodide acts as an anticholinergic compound with inhibitory activity. Also acts as a muscarinic receptor antagonist which can be applied to treatment of diseases affecting cognition including Alzheimer’s disease.용도
Isopropamide inhibits muscarinic action of acetylcholine on postganglionic parasympathetic effector regions. It is used for treating stomach ulcers and inflamed intestine.일반 설명
Isopropamide iodide, 3-carbamoyl-3,3-diphenylpropyl)diisopropylmethylammoniumiodide (Darbid), occurs as a bitter, white to pale yellow, crystallinepowder that is only sparingly soluble in water butfreely soluble in chloroform and alcohol.This drug, introduced in 1957, is a potent anticholinergic,producing atropine-like effects peripherally. Even with itsquaternary nature, it does not cause sympathetic blockade atthe ganglionic level except at high dosages. Its principal distinguishingfeature is its long duration of action. A singledose can provide antispasmodic and antisecretory effects foras long as 12 hours.
Clinical Use
ISOPROPAMIDE IODIDE is used as adjunctive therapy in the treatment of pepticulcer and other conditions of the GI tract associated withhypermotility and hyperacidity. It has the usual side effectsof anticholinergics (dryness of mouth, mydriasis, difficulturination) and is contraindicated in glaucoma, prostatic hypertrophy,etc.Synthesis
Isopropamide, (3-carbamoyl-3,3-diphenylpropyl)di-iso-propylmethyl ammonium iodide (14.1.25), is synthesized by alkylating diphenylacetonitrile with di-isopropylaminoethylchloride in the presence of sodium amide, and the subsequent hydrolysis of the nitrile group of the resulting compound (14.1.23) to an amide group (14.1.24). Alkylation of this compound with methyliodide gives isopropamide (14.1.25) [19¨C22].
N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄 준비 용품 및 원자재
원자재
준비 용품
N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄 공급 업체
글로벌( 136)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 |
1022@dideu.com | China | 3882 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21631 | 55 |
| SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2930 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 32159 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 |
sales@afinechem.com | China | 15350 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 |
info@fortunachem.com | China | 5969 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52849 | 58 |
| Henan Alfa Chemical Co., Ltd | |
China | 13179 | 58 |
N-(3-카바모일-3,3-다이페닐프로필)-N,N-다이아이소프로필메틸암모늄 관련 검색:
(S)-Metolachlor
Propisochlor
DL-Mandelic acid
Decanedihydrazide
1,2-Ethanedithiol
diisopromine
(R)-(+)-1-(1-Naphthyl)ethylamine
ISOPROPAMIDE IODIDE
3,3-Diphenylpropylamine
2,2-DIPHENYLACETAMIDE
N-Methyl-3,3-diphenylpropylamine
4-(diisopropylamino)-2,2-diphenylbutyramide
alpha-Methylhydratropamide
(R)-2-PHENYLPROPYLAMIDE
N,N,3,3-Tetramethylbutylamine, 99%
Isopropamide iodide USP23
AMMONIUM, TRIMETHYL(3-PHENYLPROPYL)-, IODIDE