methyl orsellinate
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methyl orsellinate 속성
- 녹는점
- 141-142℃
- 끓는 점
- 339℃
- 밀도
- 1.296
- 인화점
- 138℃
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 8.27±0.23(Predicted)
- 색상
- 흰색에서 황백색까지
- InChI
- InChI=1S/C9H10O4/c1-5-3-6(10)4-7(11)8(5)9(12)13-2/h3-4,10-11H,1-2H3
- InChIKey
- NCCWCZLEACWJIN-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C1=C(C)C=C(O)C=C1O
- LogP
- 2.380 (est)
안전
| HS 번호 | 2918290090 |
|---|
methyl orsellinate C화학적 특성, 용도, 생산
용도
Methyl 2,4-Dihydroxy-6-methylbenzoate (methyl orsellinate) is a useful synthetic intermediate in the synthesis of Grifolic Acid (G786500); a selective partial GPR120 agonist. Grifolic Acid induces ERK and [Ca2+]i responses in cells expressing GPR120, but has no effects on those expressing GPR40.Biochem/physiol Actions
Methyl orsellinate, an antifungal compound, is produced during submerged culture from Sparassis crispa. Methyl orsellinate have appeared to have higher antifungal activity than sparassol. Methyl orsellinate is a phytotoxic compound; it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. It could inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM; the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity; methyl orsellinate may treat the type 2 diabetes and obesity.methyl orsellinate 준비 용품 및 원자재
원자재
준비 용품
methyl orsellinate 공급 업체
글로벌( 47)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Zhengzhou Anbu Chem Co.,Ltd | +86-0371-88006763; +8615988602810 |
sales@anbuchem.com | China | 3000 | 58 |
| Xiamen Work-For-World Medicine Co.,Ltd. | +undefined15921822462 |
keqingyong@wfwmed.com | China | 191 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| PNP Biotech Co. Ltd | +8618516098983 |
sales@pnpbiotech.com | China | 1001 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
| Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 131981 | 58 |