Tadalafil-d3
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Tadalafil-d3 속성
- 녹는점
- 281-283°C
- 저장 조건
- -20°C Freezer
- 용해도
- 클로로포름 (약간 용해됨), DMSO (약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- 안정성
- 메탄올에서는 불안정함
- InChI
- InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3
- InChIKey
- WOXKDUGGOYFFRN-PDIFIXMTNA-N
- SMILES
- c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r|
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Tadalafil-d3 C화학적 특성, 용도, 생산
개요
Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.화학적 성질
Tadalafil-d3 is White Solid용도
Tadalafil-d3 is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor. Intended for use as an internal standard for the quantification of Tadalafil by GC- or LC-mass spectrometry.Tadalafil-d3 준비 용품 및 원자재
원자재
준비 용품
Tadalafil-d3 공급 업체
글로벌( 46)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
SIMSON PHARMA LIMITED | +91-8291074273 |
k.das@simsonpharma.com | India | 228 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | -- |
info@bocsci.com | USA | 0 | 65 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
Chemsky(shanghai)International Co.,Ltd. | 021-50135380 |
shchemsky@sina.com | China | 32344 | 50 |
Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 |
han_yajun@dctc.daicel.com | China | 6818 | 65 |
Cato Research Chemicals Inc. | 020-81960175 |
min.he@cato-chem.com | China | 1958 | 55 |
ChemStrong Scientific Co.,Ltd | 0755-66853366 15920483169 |
sales@chem-strong.com | China | 17944 | 56 |
Clearsynth Canada Inc. | +1.415.685.4395 |
enquiry@clearsynth.com | Canada | 912 | 58 |
Tadalafil-d3 관련 검색:
N-Ethyl Tadalafil
Tadalafil EP impurity E
Tadalafil iMpurity D
Tadalafil EP IMpurity F
ent-Tadalafil
tadalafi
cis-ent-Tadalafil
Tadalafil iMpurity C
cis-Tadalafil
(6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
Tadalafil KetolactaM
Tadalafil iMpurity E
Tadalafil EP Impurity
Tadalafil EP IMpurity G
Tadalafil Spiro-urethane IMpurity
[13C,2H3]-Tadalafil
Tadalafil iMpurity I
Tadalafil EP IMpurity A