Sevelamer carbonate

Sevelamer carbonate 구조식 이미지
카스 번호:
845273-93-0
상품명:
Sevelamer carbonate
동의어(영문):
Sevelam;Sevelam carbonate;Sevelamer carbonate;2-Propen-1-aminepolymerwith;Sevelamer Carbonate, Technical Grade;SIM862 Sevelamer Carbonate-----25gm;2-Propen-1-amine polymer with (chloromethyl)oxiran;carbonic acid,2-(chloromethyl)oxirane,prop-2-en-1-amine;2-Propen-1-amine polymer with (chloromethyl)oxirane carbonate;Carbonic acid, compd. with 2-(chloromethyl)oxirane polymer with 2-propen-1-amine
CBNumber:
CB32128754
분자식:
C7H14ClNO4
포뮬러 무게:
211.64
MOL 파일:
845273-93-0.mol
MSDS 파일:
SDS

Sevelamer carbonate 속성

저장 조건
Room Temperature, under inert atmosphere
용해도
<4.74mg/mL in DMSO
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 옅은 베이지까지
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H412 장기적 영향에 의해 수생생물에 유해함 수생 환경유해성 물질 - 만성 구분 3 P273, P501
예방조치문구:
P273 환경으로 배출하지 마시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

Sevelamer carbonate C화학적 특성, 용도, 생산

개요

Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.

용도

Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.

Sevelamer carbonate 준비 용품 및 원자재

원자재

준비 용품


Sevelamer carbonate 공급 업체

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