2-Cyanobenzyl bromide
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2-Cyanobenzyl bromide 속성
- 녹는점
- 72-74 °C(lit.)
- 끓는 점
- 111 °C / 1.5mmHg
- 밀도
- 1.5466 (rough estimate)
- 굴절률
- 1.6550 (estimate)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 수용성
- 물에 약간 용해됨
- 용해도
- 클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨)
- 물리적 상태
- 결정질 분말 또는 덩어리
- 색상
- 흰색에서 회색 갈색
- BRN
- 742605
- InChIKey
- QGXNHCXKWFNKCG-UHFFFAOYSA-N
- CAS 데이터베이스
- 22115-41-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 34 | ||
| 안전지침서 | 26-36/37/39-45-28A | ||
| 유엔번호(UN No.) | UN 3261 8/PG 2 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 10-19-21 | ||
| 위험 참고 사항 | Corrosive | ||
| 위험 등급 | 8 | ||
| 포장분류 | II | ||
| HS 번호 | 29269090 |
2-Cyanobenzyl bromide C화학적 특성, 용도, 생산
개요
2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.화학적 성질
White to light yellow crystal powder용도
2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin, an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package.
일반 설명
2-(Bromomethyl)benzonitrile reacts with 2H-tetrazole in the presence of KOH to yield 4-[(2H-tetra-zol-2-yl)meth-yl]benzonitrile. It undergoes base-promoted condensation reaction with homophthalic anhydride to yield 6,11-dihydro-5H-indeno[1,2-c]isoquinolin-5-one.Purification Methods
Purify the nitrile by steam distillation. Extract the distillate with Et2O, dry the extract (Na2SO4), evaporate and distil the residue. The solidified distillate can be recrystallised from pet ether or cyclohexane. NMR (CDCl3) : 7.8-7.2 (m 4H), 4.62 (s, 2H), IR max 2238 cm1 . [Drory Chem Ber 24 2570 1891, Borsche et al. Chem Ber 74 685 1934, Buckley et al. Aust J Chem 22 594 1969, Beilstein 9 III 2312.] LACHRYMATORY.2-Cyanobenzyl bromide 준비 용품 및 원자재
원자재
준비 용품
2-[(6-Chloro-3,4-dihydro-3-Methyl-2,4-dioxo-1(2h)-pyriMidinyl)Methyl]benzonitrile
2-[(6-CHLORO-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)METHYL]BENZONITRILE
2-(Hydroxymethyl)benzonitrile
Dibenzo[b,e]thiepin-11(6H)-one
2,3-dihydro-1-oxo-1H-indene-4-carbonitrile
2-[(2-formylpyrrol-1-yl)methyl]benzonitrile
N-[2-(AMINOMETHYL)BENZYL]-N,N-DIETHYLAMINE
2-Cyanobenzyl acetate
2-(4-HYDROXY-PIPERIDIN-1-YLMETHYL)-BENZONITRILE
2-Cyanobenzyl bromide 공급 업체
글로벌( 516)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 |
Mandy@hangyubiotech.com | China | 11013 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 951 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ |
sales03@shyrchem.com | CHINA | 738 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |