ChemicalBook >제품 카탈로그 >1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE 구조식 이미지

카스 번호:: 866396-34-1

상품명:: 1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE

동의어(영문):: DPPI 1C HCL;DPPI 1C HYDROCHLORIDE;Dipeptidylpeptidase IV Inhibitor III - CAS 866396-34-1 - Calbiochem;2,5-Pyrrolidinedicarbonitrile, 1-[2-[[1-(hydroxymethyl)cyclopentyl]amino]acetyl]-, (2R,5S)-rel-;1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE

CBNumber:: CB32453447

분자식:: C14H20N4O2

포뮬러 무게:: 276.33

MOL 파일:: 866396-34-1.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 19

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE 속성

저장 조건: Desiccate at RT

용해도: Soluble in DMSO > 10 mM

물리적 상태: 흰색 고체

안전

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE C화학적 특성, 용도, 생산

일반 설명

An orally bioavailable dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of DPP IV (IC₅₀ = 106 nM using recombinant human DPP IV and 38, 69, 92, and 100 nM in inhibiting DPP IV activity in plasma from rat, human, monkey, and dog, respectively) with little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 μM. Reported to lower blood DPP IV activity and augment GLP-1 response in dog and mouse in vivo.

생물학적 활성

Inhibitor of dipeptidyl peptidase IV (DPP-IV) (IC 50 = 104 nM) that displays selectivity over enzymes with DPP-like activity (IC 50 > 30 μ M). Increases plasma GLP-1 levels and improves glucose tolerance in diabetic mice following oral glucose challenge.

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE 준비 용품 및 원자재

원자재

준비 용품

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE 공급 업체

글로벌( 19)공급 업체

공급자	전화	이메일	국가	제품 수	이점
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Absin Bioscience Inc.	021-38015121 15000105423	chenjw@absin.cn	China	24734	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24131	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE 관련 검색:

(S)-Pyrrolidine-2-carbonitrile hydrochloride (S)-PYRROLIDINE-2-CARBONITRILE (R)-PYRROLIDINE-2-CARBONITRILE HYDROCHLORIDE 1-[[[(1-HYDROXYMETHYL)CYCLOPENTYL]AMINO]ACETYL]-2,5-CIS-PYRROLIDINEDICARBONITRILE HYDROCHLORIDE