Toceranib
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Toceranib 속성
- 녹는점
- >133°C (dec.)
- 끓는 점
- 596.8±50.0 °C(Predicted)
- 밀도
- 1.293
- 저장 조건
- room temp
- 용해도
- DMSO(약간 용해됨, 가열), 메탄올(아주 적은 양으로 녹여라, 가열)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 11.70±0.20(Predicted)
- 색상
- 노란색에서 주황색으로
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Toceranib C화학적 특성, 용도, 생산
용도
Toceranib is a multitargeted indolinone receptor tyrosine kinase (RTK) inhibitor. Toceranib exhibited activity against a variety of spontaneous malignancies in canine such as mast cell tumors, mixed m ammary carcinomas, soft tissue sarcomas, and multiple myeloma.Biochem/physiol Actions
Toceranib (SU11654) is a protein tyrosine kinase inhibitor that selectively targets stem cell factor receptor c-kit, including all forms of mutant Kit, as well as PDGFR and VEGFR. Toceranib exhibited Ki values of 5 nM for PDGFR and 6 nM for VEGFR. Toceranib phosphate is approved for use in mast cell cancer in dogs.Toceranib 준비 용품 및 원자재
원자재
1H-Pyrrole-3-carboxamide, 5-formyl-2,4-dimethyl-N-[2-(1-pyrrolidinyl)ethyl]-
Ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
5-플루오로-2-옥신돌
5-((Z)-(5-Fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
3,5-Dimethylpyrrole-2,4-dicarboxylic acid 2-t-butyl ester-4-ethyl ester
2-아미노에틸-1-피롤리딘
준비 용품
Toceranib 공급 업체
글로벌( 112)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 |
info@afinechem.com | CHINA | 15377 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 |
trendseenbio@gmail.com | China | 11681 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 |
info@gihichemicals.com | China | 49999 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8474 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 |
product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |