Guanabenz is an α2-adrenergic agonist that exhibits pronounced hypotensive action, and
that is associated with a reduction of overall peripheral vascular resistance, decline in frequency
of cardiac contractions, and reduced cardiac output.
용도
alpha agonists
Purification Methods
Crystallise the guanidine from MeCN and store it in a CO2–free atmosphere. The monoHCl [23256-5-0] has m 178o(dec) [solubility w% at 25o is 1.1(H2O), 5(EtOH), 0.1(EtOAc), 0.06(CHCl3)]. It is an antihypertensive drug. [Holmes et al. Drugs 26 212 1983.]
