Creatine phosphate

Creatine phosphate 구조식 이미지
카스 번호:
67-07-2
상품명:
Creatine phosphate
동의어(영문):
phosphocreatine;2-(1-Methyl-3-phosphonoguanidino)acetic acid;Glycine, N-[imino(phosphonoamino)methyl]-N-methyl-;Neoton;phosphagen;n-phosphocreatine;CREATINE PHOSPHATE;N-Phosphorocreatine;Creatine phosphoric acid;Creatine phosphate USP/EP/BP
CBNumber:
CB3266807
분자식:
C4H10N3O5P
포뮬러 무게:
211.11
MOL 파일:
67-07-2.mol

Creatine phosphate 속성

녹는점
>175oC (dec.)
끓는 점
449.1±47.0 °C(Predicted)
밀도
1.83±0.1 g/cm3(Predicted)
저장 조건
Hygroscopic, -20°C Freezer, Under inert atmosphere
용해도
에 용해됨물
산도 계수 (pKa)
pKa 4.7± 0.01(H2O,t =25)(Approximate)
물리적 상태
고체
물리적 상태
단단한 모양
색상
흰색에서 황백색까지
안정성
흡습성
CAS 데이터베이스
67-07-2(CAS DataBase Reference)
EPA
Glycine, N-[imino(phosphonoamino)methyl]-N-methyl- (67-07-2)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2 0

Creatine phosphate C화학적 특성, 용도, 생산

용도

Phosphocreatine used in the synthesis of hydroxypatite nanorod/nanosheets. Phosphocreatine is used in the treatment of heart and brain ischemia.

효소 저해제

This phosphagen (FW = 211.11 g/mol; CAS 67-07-2; 922-32-7 for disodium salt), known almost as commonly as creatine phosphate, is the primary cytosolic phosphoryl donor for the resynthesis of MgATP from MgADP through the action of creatine kinase in vertebrates and some invertebrates. While abundant in skeletal and cardiac muscle (40-60 mM), nonmuscle cells contain 3-5 mM, and some fungi (e.g., Candida) have intermediate levels of this metabolite. Note: The reported inhibitory action by creatine kinase is often due to impurities (e.g., the inhibition of 5’- nucleotidase is due to an impurity in the commercial phosphocreatine). The reported inhibition of AMP deaminase is due mainly to the presence of pyrophosphate. Phosphocreatine is a hygroscopic solid and very soluble in water. Unstable in acid, all is hydrolyzed after one minute at 100°C in 1.0 M HCl, and half is hydrolyzed in 4 min at 25°C in 0.5 M HCl. Molybdate and certain buffers reportedly accelerate hydrolysis. Hydrolysis is slow under slightly alkaline conditions (e.g., pH 7.8). Nevertheless, solutions should always be freshly prepared and stored frozen. Target(s): adenylate cyclase; AMP deaminase; glutamine synthetase; H+-extrusion by plasma membrane ATPase; NADH peroxidase; phosphofructokinase; and thiamin-phosphate diphosphorylase.

Creatine phosphate 준비 용품 및 원자재

원자재

준비 용품


Creatine phosphate 공급 업체

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