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피리독살 하이드로클로라이드

피리독살 하이드로클로라이드
피리독살 하이드로클로라이드 구조식 이미지
카스 번호:
65-22-5
한글명:
피리독살 하이드로클로라이드
동의어(한글):
피리독살하이드로클로라이드;피리독살 하이드로클로라이드
상품명:
Pyridoxal hydrochloride
동의어(영문):
PL HCL;PYRIDOXAL HCL;TIMTEC-BB SBB000425;Pyridoxal hydrochlor;Pyridoxine Impurity 22;PYRIDOXAL HYDROCHLORIDE;PyridoxalHydrochloride>Pyridoxalhydrochloride,99%;Pyridoxal hydrochloride(PLC);Pyridoxal-[2H3] hydrochloride
CBNumber:
CB3271476
분자식:
C8H10ClNO3
포뮬러 무게:
203.62
MOL 파일:
65-22-5.mol

피리독살 하이드로클로라이드 속성

녹는점
173 °C (dec.)(lit.)
저장 조건
2-8°C
물리적 상태
Powder
색상
White
수용성
Soluble in water and ethanol.
감도
Hygroscopic
Merck
14,7978
BRN
3656994
InChIKey
FCHXJFJNDJXENQ-UHFFFAOYSA-N
CAS 데이터베이스
65-22-5(CAS DataBase Reference)
EPA
Pyridoxal hydrochloride (65-22-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 20/21/22-36/37/38
안전지침서 24/25-22-36-26
WGK 독일 2
RTECS 번호 UV1225000
F 고인화성물질 8
TSCA Yes
HS 번호 29362500
그림문자(GHS):
신호 어:
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H303 삼키면 유해할 수 있음 급성 독성 물질 - 경구 구분 5 P312
예방조치문구:

피리독살 하이드로클로라이드 C화학적 특성, 용도, 생산

화학적 성질

White to off-white crystalline powder

용도

For the labeling of amino acids and their detection in picomolar amounts1; Coenzymes and Cofactors, vol. 1: Vitamin B6, Pyridoxal Phosphate2

용도

Pyridoxal is one of the three natural forms of vitamin B6, along with pyridoxamine and pyridoxine. All of these forms are converted in the human body into a single biologically active form, Pyridoxal 5-phosphate (P991715). Green plants are a natural source of Pyridoxal, and its deficiency in the human body can lead to serious complications such as epilepsy and seizures.

용도

Pyridoxal hydrochloride is used in labeling of amino acids for their detection. It finds application in neurotransmitters, sphingolipids and aminolevulinic acid. It is also used as a nutritional agent. It is also applied in research studies like biochemical, drugs and in media supplements.

정의

ChEBI: A hydrochloride obtained by combining pyridoxal with one molar equivalent of hydrochloric acid.

일반 설명

Pyridoxal is a heterocyclic compound, weighing 167.2 Da. It is one of the natural forms of vitamin B6. Pyridoxal is found to be less stable than pyridoxine, hence heating might result in the loss of its action. Pyridoxal has a wide variety of sources and is present in both plants and animals. Pyridoxal serves as an efficient precursor for coenzymes : pyridoxal phosphate and pyridoxamine phosphate.

Biochem/physiol Actions

Vitamin B6 plays a key role in metabolism of both carbohydrates and amino acids. It is implicated in the synthesis of neurotransmitters like dopamine from L-DOPA, serotonin from 5-HTP, and γaminobutyric acid (GABA) from glutamate. Vitamin B6 plays a major role in maintenance of a healthy nervous system.

Safety Profile

Poison by intramuscular, intravenous, and intraperitoneal routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl. See also ALDEHYDES.

Purification Methods

Dissolve it in water and adjust the pH to 6 with NaOH. Set aside overnight to crystallise. The crystals are washed with cold water, dried in a vacuum desiccator over P2O5 and stored in a brown bottle at room temperature. The free base is then converted to the hydrochloride with one equivalent of HCl. [Fleck & Alberty J Phys Chem 66 1678 1962, Beilstein 21/13 V 44.]

피리독살 하이드로클로라이드 준비 용품 및 원자재

원자재

준비 용품


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