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Mosapride

Mosapride 구조식 이미지

카스 번호:: 112885-41-3

상품명:: Mosapride

동의어(영문):: Moza;Mosapid;TAK-370;Mosid-MT;MOSAPRIDE;Mosapride reference;Mosapride USP/EP/BP;((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide/mosapride;4-AMINO-5-CHLORO-2-ETHOXY-N-((4-(4-FLUOROBENZYL)-2-MORPHOLINYL)METHYL)BENZAMIDE;4-AMINO-5-CHLORO-2-ETHOXY-N-[4-(4-FLUORO-BENZYL)-MORPHOLIN-2-YLMETHYL]-BENZAMIDE

CBNumber:: CB3273304

분자식:: C21H25ClFN3O3

포뮬러 무게:: 421.89

MOL 파일:: 112885-41-3.mol

속성

안전

용도

공급 업체 185

Mosapride 속성

녹는점: 151-153°C

끓는 점: 549.2±50.0 °C(Predicted)

밀도: 1.272±0.06 g/cm3(Predicted)

저장 조건: Keep in dark place,Sealed in dry,Room Temperature

용해도: DMSO(약간 용해됨), 메탄올(약간 용해됨)

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 13.52±0.46(Predicted)

색상: 흰색에서 황백색까지

CAS 데이터베이스: 112885-41-3(CAS DataBase Reference)

안전

Mosapride C화학적 특성, 용도, 생산

개요

Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.

화학적 성질

White to Off-White Crystalline Solid

용도

A selective 5-HT4 receptor agonist. Gastroprokinetic.

위험도

A poison by ingestion.

Safety Profile

A poison by ingestion. When heated to decomposition it emits toxic vapors of NOx, F-, and Cl-.

Mosapride 준비 용품 및 원자재

원자재

준비 용품

Mosapride citrate

Mosapride 공급 업체

글로벌( 185)공급 업체

공급자	전화	이메일	국가	제품 수	이점
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
Shaanxi Dideu Medichem Co. Ltd	+86-029-89586680 +86-18192503167	1026@dideu.com	China	9358	58
Chongqing Ensky Pharmaceutical Co.,Ltd.	+86-23-86815286 +86-13983794297	sales@ensky-chemical.com	China	87	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29271	58

Mosapride 관련 검색:

4-AMINO-5-CHLORO-2-ETHOXY-N-[[4-(4-FLUOROBENZYL)-2-MORPHOLINYL]METHYL]BENZAMIDE CITRATE DIHYDRATE Mosapride Impurity 3 Mosapride Impurity 6 Mosapride Impurity 7 4-amino-5-chloro-2-ethoxy-N-((2-morpholinyl)methyl)benzamide Mosapride Impurity 8 Mosapride Impurity 2 Mosapride Citric Amide Mosapride N-Oxide Des-4-fluorobenzyl Mosapride-d5 Mosapride Impurity 4 Mosapride Lactose Conjugate Mosapride Impurity 1 5-Amino-4-chloro-2-methylphenol 3-Hydroxyazetidine hydrochloride 2-(4-FLUOROBENZYLAMINO)ETHANOL 4-[(4-Fluorophenyl)methyl]-2-morpholinemethanamine (4-BENZYL-1,4-OXAZINAN-2-YL)METHYLAMINE