알에이치-올리고펩타이드-1

알에이치-올리고펩타이드-1 속성

알에이치-올리고펩타이드-1 C화학적 특성, 용도, 생산

개요

An ophthalmic formulation of epidermal growth factor (urogastrone) has been launched for stimulation of healing of the corneal epithelium following various corneal diseases.

화학적 성질

Endotoxin < 0.1 ng per μg (1EU/ug) of EGF

용도

Epidermal Growth Factor, human, animal component free has been used:

• as a supplement in in LHC-8 medium to culture liver cell lines
• in the fetal bovine serum (FBS)-Dulbecco′s modified essential medium (DMEM) /F12 medium for primary culture of human glioma cells
• as an additive in the conditional medium of normal fibroblasts (NFs) to study its effect on the migration and invasion of endometrial cancer (EC) cells
• as a component in tumorsphere medium

주요 응용

Epidermal Growth Factor (EGF) is a human protein that is involved in the regulation of cell growth, differentiation and survival. Recombinant EGF is an antigen binding molecule that can be used as a cancer treatment. Recombinant EGF has been shown to stimulate cellular transformation by binding to the epidermal growth factor receptor. It also has been shown to inhibit the growth of breast cancer cells with the HER2 gene mutation. The molecular weight of rec EGF is approximately 25 kDa and is composed of 165 amino acids. Recombinant EGF can be used in immunoassays, as a model system for studying biological properties, or as an antibody production tool.

일반 설명

Epidermal Growth Factor (EGF) is a small mitogenic polypeptide (～6 kDa), which is present in many mammalian species and is distributed throughout a wide number of tissues and body fluids.^? Human EGF is identical to β-urogastrone, a polypeptide which was recognized and isolated on the basis of its ability to inhibit gastric acid secretion.^? EGF is a member of a growth factor family, which is characterized by the presence of 6 conserved cysteine motifs that form three disulfide bonds. The location of 3 intrachain disulfide bonds in recombinant human EGF is identical to that of mouse EGF.^? EGF is homologous to a sequence contained in a 19 kDa protein of vaccinia virus,^? which appears to utilize the EGF receptor to gain entry into cell? EGF is mitogenic for a variety of epidermal and epithelial cells, including fibroblasts, glial cells, mammary epithelial cells, vascular and corneal endothelial cells, bovine granulosa, rabbit chondrocytes, HeLa cells, and SV40-3T3 cells.^?

알에이치-올리고펩타이드-1 준비 용품 및 원자재

원자재

준비 용품

알에이치-올리고펩타이드-1 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Tengmao Chemical Technology Co. LTD	+8615238638457	salesvip2@hntmhg.com	China	415	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Rixing Chemical CO.,LTD	+86-13237129059 -13237129059	sales@rixingchemi.com	CHINA	229	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
.GZ HONESTCHEM CO.,LTD	+86-15013270415	honestchemical@foxmail.com	China	247	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58

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