ANTI-SHPS-1

ANTI-SHPS-1 C화학적 특성, 용도, 생산

용도

Anti-SIRPα1 may be used in immunoblotting application at a working concentration of 4 μg/mL using mouse myeloblast whole cell lysate. The antibody is suitable for protein microarray and immunoprecipitation.

일반 설명

Signal regulatory proteins (SIRPs) are a class of transmembrane glycoproteins with extracellular domains resembling the immunoglobulins. The SIRP family consists of three members, SIRPα, SIRPβ and SIRPγ. In rat there are two SIRPβ members, SIRPβ1 and SIRPβ2. SIRP members are ubiquitously present on the surface of all immune system cells. SIRPα (SHP-1) is expressed on neurons, myeloid dendritic cells, mast cells, macrophages and granulocytes. The most studied role of SIRPα is the inhibition of host cell phagocytosis by the macrophages. SIRPα is reportedly involved in clearance of aged erythrocytes, regulation of production of TNF-α induced by LPS, controlling the migration of myeloid cells and maturation of dendritic cells
Anti-SIRPα1 (SHPS-1) recognizes the differentially glycosylated forms of SIRPα1(SHPS-1) of 130, 100 and 65 kDa. It also detects a single band at 50 kDa.

ANTI-SHPS-1 준비 용품 및 원자재

원자재

준비 용품

ANTI-SHPS-1 공급 업체

공급자	전화	이메일	국가	제품 수	이점
Riedel-de Haen AG	--		United States	6825	87
SIGMA-RBI	--		Switzerland	6913	91
EMD Biosciences, Inc.	--	technical@calbiochem.com	United States	6529	66
VWR International	--	solutions@vwr.com	United Kingdom	6554	82
BIOTREND Chemikalien GmbH	--	jaeger@biotrend.com	Germany	6115	76
BD Biosciences	--		United States	5013	82
Upstate	--	info@upstate.com	United States	876	76
Novus Biologicals, Inc.	--	novus@novusbio.com	United States	175	77
ABR-Affinity BioReagents	--	affinity@bioreagents.com	United States	489	73