깁(인간)
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깁(인간) 속성
- 저장 조건
- −20°C
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- White to off-white
- 수용성
- Soluble to 1 mg/ml in water
- 시퀀스
- H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-His-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
안전
WGK 독일 | 3 |
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깁(인간) C화학적 특성, 용도, 생산
개요
GIP was originally isolated as a gastric inhibitory polypeptide. After the discovery of its glucose-dependent insulinotropic activity, known as the incretin effect, GIP was renamed glucose-dependent insulinotropic peptide.Gastric inhibitory peptide
Abbreviation: GIP
Additional names: gastric inhibitory polypeptide,gastrointestinal inhibitory peptide, glucose-dependent, insulinotropic peptide
화학적 성질
Human GIP: Mr 4983.6, theoretical pI 6.92. GIP is soluble in water, but insoluble in ethanol. GIP is inactivated by DPP-4.역사
GIP was originally isolated from the porcine intestinal extract on the basis of its acid inhibitory activity in dogs (gastric inhibitory polypeptide) in the early 1970s, and subsequently renamed glucose-dependent insulinotropic peptide after the finding of its physiologically important role as a potentiator of glucose-stimulated insulin secretion.용도
GIP possessing incretin activity enhances glucosestimulated insulin release. GIP agonists are potentially useful for the treatment of diabetes. Moreover, DPP-4 inhibitors are approved for use in diabetes patients because GIP is rapidly deactivated by DPP-4.Biosynthesis
The expression of GIP is regulated by nutrients. The administration of glucose and lipid into the rat gastrointestinal tract increases GIP mRNA levels. Circulating GIP levels are low in the fasted state and increase within minutes of food ingestion. The postprandial levels of circulating GIP are dependent on meal size. The degree to which nutrients regulate GIP secretion is speciesdependent. Fat is a more potent stimulator than carbohydrates in humans, whereas in the rodent and pig, carbohydrates are more potent than fat. Once released, GIP is rapidly deactivated by DPP-4.깁(인간) 준비 용품 및 원자재
원자재
준비 용품
깁(인간) 공급 업체
글로벌( 110)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Wuhan senwayer century chemical Co.,Ltd | +undefined-27-86652399 +undefined13627115097 |
market02@senwayer.com | China | 903 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 |
sales@alabiochem.com | China | 884 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10311 | 58 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 |
info@longyupharma.com | China | 2534 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 |
info@cellmano.com | China | 999 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29822 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 |
sales1@gotopbio.com | CHINA | 2609 | 58 |
Alfa Chemistry | |
Info@alfa-chemistry.com | United States | 24072 | 58 |
깁(인간) 관련 검색:
실버 아세틸아세토네이트 코발트(II) 아세틸아세토네이트 하이드레이트 아세틸아세톤산 구리 알루미늄 아세틸아세토네이트 아세틸아세토산 제2철 디스프로슘 트리(2,2,6,6-테트라메틸-3,5-헵탄디오네이트)
PHENYLSELENOL
DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
Tosylmethyl isocyanide
Ethyl isocyanoacetate
1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE
METHYL ISOCYANOACETATE
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)
TERT-BUTYL ISOCYANIDE
SALCOMINE
Tris(2,4-pentanedionato)chroMiuM(III)
N-BUTYLISOCYANIDE
GIP (Gastric Inhibitory polypeptide)