카르요필렌(베타)

카르요필렌(베타)
카르요필렌(베타) 구조식 이미지
카스 번호:
87-44-5
한글명:
카르요필렌(베타)
동의어(한글):
카르요필렌(베타);베타-카리오필렌
상품명:
β-Caryophyllene
동의어(영문):
CARYOPHYLLENE;β-Caryophyllene;TRANS-CARYOPHYLLENE;B-CARYOPHYLLENE;β-caryophyllen;β-caryophyllen;(E)-Caryophyllene;1-caryophyllene;Bicyclo7.2.0undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R,4E,9S)-;L-Caryophyllene
CBNumber:
CB3414149
분자식:
C15H24
포뮬러 무게:
204.35
MOL 파일:
87-44-5.mol
MSDS 파일:
SDS

카르요필렌(베타) 속성

녹는점
<25℃
알파
D -8 to -9° (chloroform)
끓는 점
129-130 °C/14 mmHg (lit.)
밀도
0.901 g/mL at 25 °C (lit.)
증기압
6Pa at 20℃
FEMA
2252 | BETA-CARYOPHYLLENE
굴절률
n20/D 1.5(lit.)
인화점
205 °F
저장 조건
-20°C
용해도
클로로포름(난용성), DMSO (약간 용해됨), 메탄올 (약간 용해됨)
색상
무색
Specific Gravity
0.90
냄새
100.00%에서. 달콤한 우디 스파이스 클로브 드라이
?? ??
매운
optical activity
[α]23/D 7.5°, neat
수용성
88μg/L at 20℃
Merck
14,1875
JECFA Number
1324
BRN
2044564
안정성
감광성
LogP
6.23 at 25℃
CAS 데이터베이스
87-44-5(CAS DataBase Reference)
EPA
Bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene-, (1R,4E,9S)- (87-44-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험 카페고리 넘버 36/37/38
안전지침서 26-36-24/25
유엔번호(UN No.) UN1230 - class 3 - PG 2 - Methanol, solution
WGK 독일 1
RTECS 번호 DT8400000
HS 번호 29021990
기존화학 물질 KE-34581
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H304 삼켜서 기도로 유입되면 치명적일 수 있음 흡인 유해성물질 구분 1 위험 GHS hazard pictograms
H317 알레르기성 피부 반응을 일으킬 수 있음 피부 과민성 물질 구분 1 경고 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P272 작업장 밖으로 오염된 의복을 반출하지 마시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P302+P352 피부에 묻으면 다량의 물로 씻으시오.
P331 토하게 하지 마시오.
NFPA 704
1
0 0

카르요필렌(베타) C화학적 특성, 용도, 생산

화학적 성질

Clear colorless liquid

출처

Three isomers (α-, β-, and γ-caryophyllene) are found in nature. The β-isomer is the most frequently encountered and most abundant. This sesquiterpene hydrocarbon occurs naturally in approximately 60 essential oils, mainly in that of cloves, from which it was originally isolated. The chemical structure has been thoroughly studied; other studies have been conducted on the isolation and the dipolar moment, as well as on its oxide. Reported found in lime peel oil, lemon, grapefruit, guava fruit, raspberry, black currant, carrot, celery seed, cinnamon bark, anise, nutmeg, cumin seed, ginger, pepper, peppermint oil, mace, laurel and caraway herb.

용도

β-Caryophyllene is notable for having a cyclobutane ring, a rarity in nature. β-Caryophyllene is one of the chemical compounds that contributes to the spiciness of black pepper. β-Caryophyllene was shown to selectively bind to the cannabinoid receptor type-2 (CB2) and to exert significant cannabimimetic antiinflammatory effects in mice.

제조 방법

Isolated from oil of clove stems and separated from eugenol by treating the oil with 7% sodium carbonate solution, extracting with ether, repeating the carbonate treatment on the concentrated extracts, and finally steam distilling.

정의

ChEBI: A beta-caryophyllene in which the stereocentre adjacent to the exocyclic double bond has S configuration while the remaining stereocentre has R configuration. It is the most commonly occurring form of <greek beta-caryophyllene, occurring in many essential oils, particularly oil of cloves.

일반 설명

Pale yellow oily liquid with an odor midway between odor of cloves and turpentine.

공기와 물의 반응

Insoluble in water.

반응 프로필

The unsaturated aliphatic hydrocarbons, such as BETA-CARYOPHYLLENE, are generally much more reactive than the alkanes. Strong oxidizers may react vigorously with them. Reducing agents can react exothermically to release gaseous hydrogen. In the presence of various catalysts (such as acids) or initiators, compounds in this class can undergo very exothermic addition polymerization reactions.

화재위험

BETA-CARYOPHYLLENE is combustible.

Safety Profile

A skin irritant. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes.

Carcinogenicity

Caryophyllene showed significant activity as an inducer of the detoxifying enzyme glutathione S-transferase in the mouse liver and small intestine. The ability of natural anticarcinogens to induce detoxifying enzymes has been found to correlate with their activity in the inhibition of chemical carcinogenesis (253a).

카르요필렌(베타) 준비 용품 및 원자재

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