5-플루오로-2-옥신돌
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5-플루오로-2-옥신돌 속성
- 녹는점
- 143-147 °C (lit.)
- 끓는 점
- 307.2±42.0 °C(Predicted)
- 밀도
- 1.311±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 12.99±0.20(Predicted)
- 물리적 상태
- 분말 또는 결정성 분말
- 색상
- 흰색에서 옅은 갈색까지
- InChIKey
- DDIIYGHHUMKDGI-UHFFFAOYSA-N
- CAS 데이터베이스
- 56341-41-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-34 | ||
| 안전지침서 | 22-24/25-45-36/37/39-27-26 | ||
| WGK 독일 | 3 | ||
| 위험 참고 사항 | Irritant/Keep Cold | ||
| 위험 등급 | IRRITANT, KEEP COLD | ||
| HS 번호 | 29339900 |
5-플루오로-2-옥신돌 C화학적 특성, 용도, 생산
화학적 성질
Light Yellow Crystalline용도
5-Fluoro-2-oxindole (cas# 56341-41-4) is a compound useful in organic synthesis.주요 응용
5-Fluoro-2-oxindole is a ketone organic compound that can be used as an intermediate in the preparation of sunitinib. Sunitinib is a novel multi-targeted oral drug for the treatment of tumors.제조 방법
synthesis of 5-fluoro-2-oxindole: 4-fluoroaniline was used as the starting material, reacted with chloral hydrate and hydroxylamine hydrochloride to generate 4-fluoroisonitrosoacetanilide, and then cyclized under the action of concentrated sulfuric acid to form the compound 5-fluoroisatin was finally obtained by wolff-kishner-huang minlon reduction to obtain 5-fluoro-2-oxindole with a total yield of 66%.5-플루오로-2-옥신돌 준비 용품 및 원자재
원자재
디플로로니트로벤젠(2,4-)
수소화나트륨
말론산 디메틸
다이메틸 설폭사이드
철분
염화 리튬
1-hydroxy-3H-indol-2-one
Ethyl iodoacetate
4-FLUOROISONITROSOACETANILIDE
5-Fluoro-3-hydrazonoindolin-2-one
2-(2-aMino-5-fluorophenyl)acetohydrazide
5-Fluoro-2-nitrophenylacetic acid
Benzeneacetic acid, 5-fluoro-2-nitro-, Methyl ester
5-플루오로이사틴
4-Fluoroacetanilide
메틸티오아세트산에틸에스테르
터르트-부틸 하이포클로라이트
준비 용품
5-플루오로-2-옥신돌 공급 업체
글로벌( 608)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Allfluoro pharmaceutical co. ltd. | 021-26137118 +8615821363818 |
sales@allfluoro.com | China | 5791 | 58 |
| Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 |
info@senovatech.com | China | 350 | 58 |
| Shanghai QiXin New Materials Technology Co.,Ltd | +8615116235351 |
derrickguo@sh-qixin.cn | China | 16 | 58 |
| Golden Pharma Co., Limited | +undefined18958062155 |
sales@zjgoldpharm.com | China | 5905 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12470 | 58 |
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 1000 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 16801 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |