티타노센 디염화물
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티타노센 디염화물 속성
- 녹는점
- 260-280 °C (dec.)(lit.)
- 끓는 점
- 355.52°C (estimate)
- 밀도
- 1.6 g/mL at 25 °C(lit.)
- 증기압
- 0.002Pa at 25℃
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- slightly soluble in H2O, benzene; soluble in chloroform,ethanol, toluene
- 물리적 상태
- 수정 같은
- 색상
- 빨간색
- Specific Gravity
- 1.6
- 수용성
- 느린 분해
- 감도
- Air & Moisture Sensitive
- Hydrolytic Sensitivity
- 4: no reaction with water under neutral conditions
- Merck
- 14,9482
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다. 물에서 분해됩니다. 수분에 민감합니다.
- LogP
- -1.35 at 20℃
- CAS 데이터베이스
- 1271-19-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,T | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 37/38-61-40-34-33-36/37/38 | ||
| 안전지침서 | 36-7/8-6A-45-36/37/39-26 | ||
| 유엔번호(UN No.) | UN3261 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | XR2050000 | ||
| F 고인화성물질 | 8-10-21 | ||
| TSCA | Yes | ||
| 위험 등급 | 8 | ||
| 포장분류 | II | ||
| HS 번호 | 29310095 | ||
| 유해 물질 데이터 | 1271-19-8(Hazardous Substances Data) | ||
| 독성 | Titanocene dichloride may cause skin and mucous membrane irritation. The LD50 in mice has been reported as 60 mg/kg (i.p.) and 180 mg/kg (i.v.). In the rat, the LD50 is 25 mg/kg (i.p.). | ||
| 기존화학 물질 | KE-10269 |
티타노센 디염화물 C화학적 특성, 용도, 생산
개요
Titanocene dichloride is an organotitanium compound with the chemical formula (η5-C5H5)2TiCl2, often written as Cp2TiCl2, which is a common reagent in organometallic chemistry and organic synthesis. Cp2TiCl2 does not form a "sandwich" structure like ferrocene, but a tetrahedral structure due to its four ligands around a metal center. Because of its anti-tumor activity, it has been used in clinical trials as a chemotherapeutic agent.
화학적 성질
Titanocene dichloride is a reddish-orange crystalline solid. Moderately soluble in toluene, chloroform, alcohol, and other hydroxylic solvents; sparingly soluble in water, petroleum ether, benzene, ether, carbon disulfide, and carbon tetrachloride. Stable in dry air, slowly hydrolyzed in moist air. Titanocene dichloride is irritating to the skin and mucous membranes.용도
Titanocene dichloride is used as an experimental cancer chemotherapeutic agent. It is used as a research chemical, as a catalyst in Ziegler–Natta polymerization reactions, and as an implant material in orthopedics, oral surgery, and neurosurgery.This metallocene is a common reagent in organometallic and organic synthesis. Titanocene dichloride is used to prepare titanocene pentasulfide. Used as an anticancer drug.생산 방법
Titanocene dichloride is produced by the reaction of titanium tetrachloride with cyclopentadienyl sodium.일반 설명
Titanocene dichloride appears as red to red-orange crystals. (NTP, 1992)공기와 물의 반응
Stable in dry air. Decomposes in moist air and in water to form HCl .반응 프로필
Titanocene dichloride is incompatible with strong oxidizers. Titanocene dichloride may decompose on exposure to water. .위험도
Toxic by inhalation, irritant to skin and mucous membranes.화재위험
Flash point data for Titanocene dichloride are not available; however, Titanocene dichloride is probably combustible.Safety Profile
Poison by intravenous and intraperitoneal routes. Questionable carcinogen with experimental neoplastigenic, tumorigenic, and teratogenic data. Mutation data reported. See also TITANIUM COMPOUNDS. When heated to decomposition it emits toxic fumes of Cl-Purification Methods
It forms bright red crystals from toluene or xylene/CHCl3 (1:1) and sublimes at 190o/2mm. It is moderately soluble in EtOH and insoluble in Et2O, *C6H6, CS2, CCl4, pet ether and H2O. The crystalline dipicrate explodes on melting at 139-140o. [Wilkinson et al. J Am Chem Soc 75 1011 1953, IR: Wilkinson & Birmingham J Am Chem Soc 76 4281 1954, NMR and X-ray: Glivicky & McCowan Can J Chem 51 2609 1973, Clearfield et al. J Am Chem Soc 53 1622 1975, Beilstein 16 IV 1769.]티타노센 디염화물 준비 용품 및 원자재
원자재
2-Butanone, 3,3-dimethyl-, 2-(2,4-dinitrophenyl)hydrazone
BIS(CYCLOPENTADIENYL)DIFLUOROTITANIUM(IV)
Bis(cyclopentadienyl)dimethyltitanium
준비 용품
티타노센 디염화물 공급 업체
글로벌( 305)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| WUXI HONOR SHINE CHEMICAL CO.,LTD | 0510-83593312 +8613665125081 |
sales@honorshinechem.com | China | 61 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7377 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 |
sales@fluoropharm.com | China | 1290 | 60 |
| Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 559 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |