FMOC-LYS(BOC)(ME)-OH
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FMOC-LYS(BOC)(ME)-OH 속성
- 녹는점
- 85-87℃
- 끓는 점
- 665.4±55.0 °C(Predicted)
- 밀도
- 1.200
- 저장 조건
- -20°C
- 용해도
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 3.88±0.21(Predicted)
- 색상
- White to off-white
- InChIKey
- JHMSFOFHTAYQLS-QHCPKHFHSA-N
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
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WGK 독일 | WGK 2 water endangering | ||
HS 번호 | 2924 29 70 |
그림문자(GHS): | |||||||||||||||||||||||||||||
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신호 어: | Warning | ||||||||||||||||||||||||||||
유해·위험 문구: |
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예방조치문구: |
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FMOC-LYS(BOC)(ME)-OH C화학적 특성, 용도, 생산
개요
Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.용도
- Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
- Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
- Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.
일반 설명
Fmoc protected N-methylated lysine참고 문헌
http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htmhttps://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.
FMOC-LYS(BOC)(ME)-OH 준비 용품 및 원자재
원자재
준비 용품
FMOC-LYS(BOC)(ME)-OH 공급 업체
글로벌( 135)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 |
sales@alabiochem.com | China | 888 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 18628 | 58 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9357 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 19536 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Chengdu Feibo Pharm Technology Co., Ltd | 15982321820 |
abby@arkpharm.com | CHINA | 3279 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
FMOC-LYS(BOC)(ME)-OH 관련 검색:
(s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide
FMoc-Aea-OH
N(ALPHA)-FMOC-N(EPSILON)-DABCYL-L-LYSINE
FMOC-LYS(DNP)-OH
Fmoc-Lys(Trt)-OH
FMOC-D-LYS(IVDDE)-OH
FMOC-LYS(ME)2-OH HCL
FMOC-LYS(ME3)-OH HCL
Fmoc-L-beta-Homoarginine(Pmc)
Fmoc-N'-Acetyl-L-lysine
Fmoc-Lys(Pal-Glu-OtBu)-OH
Fmoc-Lys(N3)-OH
FMOC-LYS(FMOC)-OH
Fmoc-L-Lys(Dde)-OH
Fmoc-Lys(Ddiv)-OH
FMOC-LYS(BOC)(ISOPROPYL)-OH
FMOC-LYS(BOC-ABZ)-OH
FMOC-LYS(BOC)-LEU-OH