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Vinorelbine

Vinorelbine 구조식 이미지
카스 번호:
71486-22-1
상품명:
Vinorelbine
동의어(영문):
CL069;F 80520;NVBKW-2307;VINORELBINE;KW 2307 base;Navelbine(R);Navelbine base;vinorelbine D-tartrate;Vinorelbine(Navelbine);5-Noranhydrovinblastine
CBNumber:
CB3469220
분자식:
C45H54N4O8
포뮬러 무게:
778.93
MOL 파일:
71486-22-1.mol

Vinorelbine 속성

알파
D20 +52.4° (c = 0.3 in CHCl3)

안전

유해 물질 데이터 71486-22-1(Hazardous Substances Data)
독성 LD50 in mice (mg/m2): 72 i.v.; 78 orally (Mathé, Reizenstein)

Vinorelbine C화학적 특성, 용도, 생산

개요

Vinorelbine is a semisynthetic vinca alkaloid differing from vinblastine in the catharantine moiety of the molecule. It is claimed to have a broad spectrum of action both in vifro and in vivo; clinically it has been found effective in the treatment of non-small cell lung cancer, advanced breast cancer, ovarian cancer and Hodgkins disease.

Originator

CNRS (France)

용도

antimigraine, 5HT[1B/1D] agonist

정의

ChEBI: A vinca alkaloid with a norvinblastine skeleton.

상표명

Navelbine (Pierre).

Clinical Use

Vinorelbine is particularly useful in the treatment of advanced non–small cell lung cancer and can be administered alone or in combination with cisplatin. It is thought to interfere with mitosis in dividing cells through a relatively specific action on mitotic microtubules.

Vinorelbine 준비 용품 및 원자재

원자재

준비 용품


Vinorelbine 공급 업체

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