17-DMAG

17-DMAG 구조식 이미지
카스 번호:
467214-21-7
상품명:
17-DMAG
동의어(영문):
KOS 1022;BMS 826476;Risatriptan;BMS 826476 HCl;AlvespiMycin HCl;MK 462 free base;17-DMAG USP/EP/BP;KOS-1022 hydrochloride;Spiramycin hydrochloride;17-DMAG (AlvespiMycin) HCl
CBNumber:
CB3469563
분자식:
C32H49ClN4O8
포뮬러 무게:
653.21
MOL 파일:
467214-21-7.mol
MSDS 파일:
SDS

17-DMAG 속성

저장 조건
Store at -20
용해도
≥26.2 mg/mL in DMSO; insoluble in EtOH; ≥3.04 mg/mL in H2O
물리적 상태
보라색 고체
InChIKey
KUFRQPKVAWMTJO-LMZWQJSESA-N

안전

HS 번호 2941900000

17-DMAG C화학적 특성, 용도, 생산

용도

17-DMAG is an analogue of Gelamycin (G304500) and 17-(Allylamino)geldanamycin (A549650). 17-DMAG acts as a Hsp90 inhibitor and displays more potent antitumor activity than 17-AAG.

효소 저해제

This potent Hsp90 inhibitor (FWHCl-Salt = 653.21 g/mol; CAS 467214-21-7), also named 17-DMAG and 17-demethoxy-17-[[2-(dimethylamino) ethyl]amino]geldanamycin, targets Heat Shock Protein-90 (IC50 = 62 nM in a cell-free assay). (See also Ansamycin; Deguelin; Derrubone; Ganetespib; Geldanamycin; Herbimycin; Macbecin; Radicicol; Tanespimycin; and the nonansamycin Hsp90 inhibitor KW-2478)

17-DMAG 준비 용품 및 원자재

원자재

준비 용품


17-DMAG 공급 업체

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