γ-Secretase Inhibitor I - Calbiochem C화학적 특성, 용도, 생산
일반 설명
A potent, cell-permeable, reversible γ-secretase inhibitor that preferentially appears to inhibit the secretion of Aβ1-40 (>90%) over Aβ1-42 (~15%). Aβtotal IC50 ~ 15 M; Aβ1-40 IC50 ~ 22 M; Aβ1-42 IC50 >50 M in CHO cells stable transfected with the cDNA encoding βAPP695.
