이소옥사졸

이소옥사졸
이소옥사졸 구조식 이미지
카스 번호:
288-14-2
한글명:
이소옥사졸
동의어(한글):
아이소옥사졸;이소옥사졸;이소카졸
상품명:
Isoxazole
동의어(영문):
ISOXAZOLE;Isooxazole;Isoxazolec;1,2-Oxazole;Isoxazole>Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole
CBNumber:
CB3485864
분자식:
C3H3NO
포뮬러 무게:
69.06
MOL 파일:
288-14-2.mol
MSDS 파일:
SDS

이소옥사졸 속성

녹는점
-67.1°C
끓는 점
93-95 °C(lit.)
밀도
1.078 g/mL at 25 °C(lit.)
증기 밀도
2.4 (vs air)
굴절률
n20/D 1.427(lit.)
인화점
48 °F
저장 조건
2-8°C
용해도
167g/L
산도 계수 (pKa)
-2.0(at 25℃)
물리적 상태
투명한 액체
색상
무색~연황색
BRN
103773
InChIKey
CTAPFRYPJLPFDF-UHFFFAOYSA-N
CAS 데이터베이스
288-14-2(CAS DataBase Reference)
NIST
Isoxazole(288-14-2)
EPA
Isoxazole (288-14-2)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 F,Xi
위험 카페고리 넘버 11
안전지침서 16-23/33-33-29-7/9
유엔번호(UN No.) UN 1993 3/PG 2
WGK 독일 3
F 고인화성물질 10
위험 참고 사항 Highly Flammable
TSCA Yes
위험 등급 3
포장분류 II
HS 번호 29349990
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H225 고인화성 액체 및 증기 인화성 액체 구분 2 위험 GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
예방조치문구:
P210 열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
NFPA 704
3
1 0

이소옥사졸 MSDS


Isoxazole

이소옥사졸 C화학적 특성, 용도, 생산

개요

Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.

화학적 성질

A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.

용도

Natural insecticide.

정의

ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.

제조 방법

Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org

일반 설명

Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.

위험도

Narcotic and psychomimetic effects.

참고 문헌

https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254

이소옥사졸 준비 용품 및 원자재

원자재

준비 용품


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